Pharmacotherapeutics applications and chemistry of chalcone derivatives
Chalcones have been well examined in the extant literature and demonstrated antibacterial,
antifungal, anti-inflammatory, and anticancer properties. A detailed evaluation of the …
antifungal, anti-inflammatory, and anticancer properties. A detailed evaluation of the …
[HTML][HTML] Exploring the synthesis, structure, spectroscopy and biological activities of novel 4-benzylidene-1-(2-(2, 4-dichloro phenyl) acetyl) thiosemicarbazide …
Background Novel α-amylase inhibitors play a crucial role in managing diabetes and
obesity, contributing to improved public health by addressing these challenging and …
obesity, contributing to improved public health by addressing these challenging and …
[HTML][HTML] A review of the in vitro inhibition of α-amylase and α-glucosidase by chalcone derivatives
Diabetes mellitus is a chronic metabolic disease relating to steady hyperglycemia resulting
from the impairment of the endocrine and non-endocrine systems. Many new drugs having …
from the impairment of the endocrine and non-endocrine systems. Many new drugs having …
Biocompatible chlorocoumarins from harmful chlorophenols, their synthesis and biomedicinal evaluation
YF Mustafa - Journal of Molecular Structure, 2024 - Elsevier
In this work, two chlorophenols with particular toxicities were transformed into their 14
corresponding coumarins (CMs). Their chemical structures were confirmed by examining the …
corresponding coumarins (CMs). Their chemical structures were confirmed by examining the …
Exploring the synthesis, molecular structure and biological activities of novel Bis-Schiff base derivatives: A combined theoretical and experimental approach
A library of six novel bis-Schiff base derivatives (2a-f) were synthesized, characterized
through modern spectroscopic techniques and screened for their α-glucosidase and α …
through modern spectroscopic techniques and screened for their α-glucosidase and α …
Synthesis of novel thiazole derivatives containing 3-methylthiophene carbaldehyde as potent anti α-glucosidase agents: In vitro evaluation, molecular docking …
Thiazole derivatives bearing thiophene carbaldehyde have been successfully prepared by
refluxing 3-methylthiophene carbaldehyde with thiosemicarbazide in absolute ethanol …
refluxing 3-methylthiophene carbaldehyde with thiosemicarbazide in absolute ethanol …
Pyrano [2, 3-b] chromone derivatives as novel dual inhibitors of α-glucosidase and α-amylase: Design, synthesis, biological evaluation, and in silico studies
E Farzaneh, M Mohammadi, P Raymand, M Noori… - Bioorganic …, 2024 - Elsevier
Inhibition of α-glucosidase and α-amylase is an important target for treatment of type 2
diabetes. In this work, a novel series of pyrano [2, 3-b] chromene derivatives 5a-m was …
diabetes. In this work, a novel series of pyrano [2, 3-b] chromene derivatives 5a-m was …
[HTML][HTML] Synthesis of modified 1, 3, 4-thiadiazole incorporating substituted thiosemicarbazide derivatives: Elucidating the in vitro and in silico studies to develop …
Hybrid molecules based on the 1, 3, 4-thiadiazole were always the choice of different
researchers due to their significant application in medicinal as well as pharmaceutical …
researchers due to their significant application in medicinal as well as pharmaceutical …
Synthesis and Molecular Docking Study of Hydrazone Schiff Bases of α‐Naphthalene‐Containing Alkyl Phenyl Ether Fragment as Potent α‐Amylase and α …
In this study, new Schiff base derivatives of α‐naphthalene acetic acid containing alkyl
phenyl ether fragment have been effectively synthesized through multistep reaction process …
phenyl ether fragment have been effectively synthesized through multistep reaction process …
Synthesis and characterization of newly phthalocyanine molecules: Their enzyme inhibition and antioxidant properties, in silico and in vitro
F Çelik, Y Ünver, F OzTuncay, U Cakmak… - Journal of …, 2024 - Elsevier
Pcs exhibiting maximum absorption in the phototherapeutic window continue to shine as a
beacon of hope in the treatment of cancer. In particular, they maintain skin sensitivity after …
beacon of hope in the treatment of cancer. In particular, they maintain skin sensitivity after …