The complexity of the blood–brain barrier (BBB) and neurovascular unit (NVU) was and still
is a challenge to bridge. A highly selective, restrictive and dynamic barrier, formed at the …

As an important functional protein molecule in the human body, human annexin A5
(hAnxA5) is widely found in human cells and body fluids. hAnxA5, the smallest type of …

Background: The current post-procedure antithrombotic recommendation for left atrial
appendage closure (LAAC) remains empiric. This study was designed to compare variations …

Brain arteriovenous malformations (AVMs) are a significant cause of intracerebral
hemorrhage in children and young adults. Currently, one third of patients have no viable …

Aims: The goal of this study was to establish a simple model of 3D endothelial spheroids
with mosaic gene expression using adeno-associated virus (AAV) transduction, with a future …

Radiation has been proposed as a priming agent to induce discriminatory luminal
biomarkers for vascular targeting and drug delivery in disorders such as brain arteriovenous …

Endothelial cells are highly sensitive to ionizing radiation, and exposure leads to multiple
adaptive changes. Remarkably, part of this response is the translocation of normally …

In cardiovascular and cerebrovascular biology, control of thrombosis and the coagulation
cascade in ischemic stroke, myocardial infarction, and other coagulopathies is the focus of …

Background Vascular targeting uses molecular markers on the surface of diseased
vasculature for ligand-directed drug delivery to induce vessel occlusion or destruction. In the …

人膜联蛋白A5 已被广泛应用于体外细胞凋亡检测, 此外, 其还具有用于心血管类疾病和炎症性
疾病等治疗的潜在价值. 膜联蛋白A5 具有多种生物学功能及潜在的应用前景 …