Background Pretreatment drug resistance in people initiating or re-initiating antiretroviral
therapy (ART) containing non-nucleoside reverse transcriptase inhibitors (NNRTIs) might …

Background Increased access to antiretroviral therapy (ART) has resulted in rising levels of
pretreatment human immunodeficiency virus drug resistance (PDR). This is the first …

Little is known about the impact of pretreatment drug resistance (PDR) on the efficacy of
second generation integrase inhibitors. We sequenced pretreatment plasma specimens …

Background The emergence and spread of HIV-1 drug resistance may compromise HIV
control globally. In response to HIV/AIDS epidemic, China launched national HIV/AIDS …

Higher accessibility and decreasing costs of next generation sequencing (NGS), availability
of commercial kits, and development of dedicated analysis pipelines, have allowed an …

Next generation sequencing (NGS) is a trending new standard for genotypic HIV-1 drug
resistance (HIVDR) testing. Many NGS HIVDR data analysis pipelines have been …

The ability of next-generation sequencing (NGS) technologies to detect low frequency HIV-1
drug resistance mutations (DRMs) not detected by dideoxynucleotide Sanger sequencing …

The rising prevalence of HIV drug resistance (HIVDR) could threaten gains made in
combating the HIV epidemic and compromise the 90-90-90 target proposed by United …

Background The presence of high-abundance drug-resistant HIV-1 jeopardizes success of
antiretroviral therapy (ART). Despite numerous investigations, the clinical impact of low …

Next-generation sequencing (NGS) is increasingly used for HIV-1 drug resistance
genotyping. NGS methods have the potential for a more sensitive detection of low …