Staphylococcus aureus lipoproteins in infectious diseases
Infections with the Gram-positive bacterial pathogen Staphylococcus aureus remain a major
challenge for the healthcare system and demand new treatment options. The increasing …
challenge for the healthcare system and demand new treatment options. The increasing …
The Mycoplasma spp. 'Releasome': A New Concept for a Long-Known Phenomenon
P Gaurivaud, F Tardy - Frontiers in Microbiology, 2022 - frontiersin.org
The bacterial secretome comprises polypeptides expressed at the cell surface or released
into the extracellular environment as well as the corresponding secretion machineries …
into the extracellular environment as well as the corresponding secretion machineries …
Acinetobacter baumannii Outer Membrane Protein A Induces Pulmonary Epithelial Barrier Dysfunction and Bacterial Translocation Through The TLR2/IQGAP1 Axis
W Zhang, H Zhou, Y Jiang, J He, Y Yao… - Frontiers in …, 2022 - frontiersin.org
Pulmonary epithelial barrier dysfunction is a critical pathophysiological process in
pneumonia and associated invasive infections, such as those caused by Acinetobacter …
pneumonia and associated invasive infections, such as those caused by Acinetobacter …
CCN1 is an opsonin for bacterial clearance and a direct activator of Toll-like receptor signaling
Expression of the matricellular protein CCN1 (CYR61) is associated with inflammation and
is required for successful wound repair. Here, we show that CCN1 binds bacterial pathogen …
is required for successful wound repair. Here, we show that CCN1 binds bacterial pathogen …
“Gene accordions” cause genotypic and phenotypic heterogeneity in clonal populations of Staphylococcus aureus
D Belikova, A Jochim, J Power, MTG Holden… - Nature …, 2020 - nature.com
Gene tandem amplifications are thought to drive bacterial evolution, but they are transient in
the absence of selection, making their investigation challenging. Here, we analyze genomic …
the absence of selection, making their investigation challenging. Here, we analyze genomic …
More is not always better—the double-headed role of fibronectin in Staphylococcus aureus host cell invasion
S Niemann, MT Nguyen, JA Eble, AI Chasan… - MBio, 2021 - Am Soc Microbiol
While Staphylococcus aureus has classically been considered an extracellular pathogen,
these bacteria are also capable of being taken up by host cells, including nonprofessional …
these bacteria are also capable of being taken up by host cells, including nonprofessional …
Lipoproteins from Staphylococcus aureus drive neutrophil extracellular trap formation in a TLR2/1-and PAD-dependent manner
JS Hook, PA Patel, A O'Malley, L Xie… - The Journal of …, 2021 - journals.aai.org
Abstract Neutrophils, polymorphonuclear leukocytes (PMN), play a critical role in the innate
immune response to Staphylococcus aureus, a pathogen that continues to be associated …
immune response to Staphylococcus aureus, a pathogen that continues to be associated …
Bacterial lipoproteins in sepsis
KV Abhilasha, GK Marathe - Immunobiology, 2021 - Elsevier
Bacterial lipoproteins are membrane proteins derived from both gram-negative and gram-
positive bacteria. They seem to have diverse functions not only on bacterial growth, but also …
positive bacteria. They seem to have diverse functions not only on bacterial growth, but also …
Staphylococcus aureus Lpl protein triggers human host cell invasion via activation of Hsp90 receptor
Staphylococcus aureus is a facultative intracellular pathogen. Recently, it has been shown
that the protein part of the lipoprotein‐like lipoproteins (Lpls), encoded by the lpl cluster …
that the protein part of the lipoprotein‐like lipoproteins (Lpls), encoded by the lpl cluster …
Organotypic 3D Co-Culture of Human Pleura as a Novel In Vitro Model of Staphylococcus aureus Infection and Biofilm Development
O Kurow, R Nuwayhid, P Stock, M Steinert, S Langer… - Bioengineering, 2023 - mdpi.com
Bacterial pleural infections are associated with high mortality. Treatment is complicated due
to biofilm formation. A common causative pathogen is Staphylococcus aureus (S. aureus) …
to biofilm formation. A common causative pathogen is Staphylococcus aureus (S. aureus) …