Dry eye disease associated with meibomian gland dysfunction: focus on tear film characteristics and the therapeutic landscape
JD Sheppard, KK Nichols - Ophthalmology and Therapy, 2023 - Springer
Meibomian gland dysfunction (MGD) is highly prevalent and is the leading cause of
evaporative dry eye disease (DED). MGD is characterized by a reduction in meibum …
evaporative dry eye disease (DED). MGD is characterized by a reduction in meibum …
Treatment of non-infectious corneal injury: review of diagnostic agents, therapeutic medications, and future targets
DH Dang, KM Riaz, D Karamichos - Drugs, 2022 - Springer
Corneal injuries can occur secondary to traumatic, chemical, inflammatory, metabolic,
autoimmune, and iatrogenic causes. Ocular infection may frequently occur concurrent to …
autoimmune, and iatrogenic causes. Ocular infection may frequently occur concurrent to …
Ocular instillation of conditioned medium from mesenchymal stem cells is effective for dry eye syndrome by improving corneal barrier function
T Imaizumi, R Hayashi, Y Kudo, X Li, K Yamaguchi… - Scientific Reports, 2023 - nature.com
Dry eye syndrome (DES) is a chronic ocular disease that induces epithelial damage to the
cornea by decreasing tear production and quality. Adequate treatment options have not …
cornea by decreasing tear production and quality. Adequate treatment options have not …
Understanding chronic ocular surface pain: an unmet need for targeted drug therapy
Chronic ocular surface pain (COSP) may be defined as a feeling of pain, perceived as
originating from the ocular surface, that persists for> 3 months. COSP is a complex …
originating from the ocular surface, that persists for> 3 months. COSP is a complex …
Impact of glaucoma medications on the ocular surface and how ocular surface disease can influence glaucoma treatment
Glaucoma is a common disease with an increasing prevalence [1]. Ocular surface disease
(OSD) is also common, and its prevalence is increasing [2, 3], due in part to the adverse …
(OSD) is also common, and its prevalence is increasing [2, 3], due in part to the adverse …
Aqueous prostaglandin eye drop formulations
P Jansook, T Loftsson - Pharmaceutics, 2022 - mdpi.com
Glaucoma is one of the leading causes of irreversible blindness worldwide. It is
characterized by progressive optic neuropathy in association with damage to the optic nerve …
characterized by progressive optic neuropathy in association with damage to the optic nerve …
Pickering emulsions stabilised with oligoglycine-functionalised nanodiamond as a model system for ocular drug delivery applications
Oil-in-water emulsions, stabilised with conventional surfactants, are commonly used in eye
drops for ocular drug delivery. However, the presence of surfactants can sometimes irritate …
drops for ocular drug delivery. However, the presence of surfactants can sometimes irritate …
Perfluorohexyloctane in dry eye disease: A systematic review of its efficacy and safety as a novel therapeutic agent
A Ballesteros-Sanchez, C De-Hita-Cantalejo… - The Ocular Surface, 2023 - Elsevier
Abstract Perfluorohexyloctane (F6H8), a physically and chemically inert synthetic
compound, has recently emerged as a promising candidate for the treatment of DED due to …
compound, has recently emerged as a promising candidate for the treatment of DED due to …
Highlighting the microbial contamination of the dropper tip and cap of in-use eye drops, the associated contributory factors, and the risk of infection: a past-30-years …
K Iskandar, L Marchin, L Kodjikian, M Rocher… - Pharmaceutics, 2022 - mdpi.com
The sterility of eye drop content is a primary concern from manufacturing until opening, as
well as during handling by end users, while microbial contamination of the dropper tip and …
well as during handling by end users, while microbial contamination of the dropper tip and …
Polyaphron formulations stabilised with different water-soluble polymers for ocular drug delivery
As drug delivery to the eye has evolved over the last decades, researchers have explored
more effective treatments for ocular diseases. Despite this, delivering drugs to the cornea …
more effective treatments for ocular diseases. Despite this, delivering drugs to the cornea …