Fluorescent nanoparticles for super-resolution imaging

W Li, GS Kaminski Schierle, B Lei, Y Liu… - Chemical …, 2022 - ACS Publications
Super-resolution imaging techniques that overcome the diffraction limit of light have gained
wide popularity for visualizing cellular structures with nanometric resolution. Following the …

Xanthene, cyanine, oxazine and BODIPY: the four pillars of the fluorophore empire for super-resolution bioimaging

S Samanta, K Lai, F Wu, Y Liu, S Cai, X Yang… - Chemical Society …, 2023 - pubs.rsc.org
In the realm of biological research, the invention of super-resolution microscopy (SRM) has
enabled the visualization of ultrafine sub-cellular structures and their functions in live cells at …

Super-resolution microscopy demystified

L Schermelleh, A Ferrand, T Huser, C Eggeling… - Nature cell …, 2019 - nature.com
Super-resolution microscopy (SRM) bypasses the diffraction limit, a physical barrier that
restricts the optical resolution to roughly 250 nm and was previously thought to be …

Deep learning enables cross-modality super-resolution in fluorescence microscopy

H Wang, Y Rivenson, Y Jin, Z Wei, R Gao… - Nature …, 2019 - nature.com
We present deep-learning-enabled super-resolution across different fluorescence
microscopy modalities. This data-driven approach does not require numerical modeling of …

BAK/BAX macropores facilitate mitochondrial herniation and mtDNA efflux during apoptosis

K McArthur, LW Whitehead, JM Heddleston, L Li… - Science, 2018 - science.org
INTRODUCTION There has been an explosion of interest in the role of cell death pathways
and damage-associated molecular pattern (DAMP) signaling in shaping inflammatory and …

Expansion microscopy: principles and uses in biological research

AT Wassie, Y Zhao, ES Boyden - Nature methods, 2019 - nature.com
Many biological investigations require 3D imaging of cells or tissues with nanoscale spatial
resolution. We recently discovered that preserved biological specimens can be physically …

Multi-color live-cell STED nanoscopy of mitochondria with a gentle inner membrane stain

T Liu, T Stephan, P Chen… - Proceedings of the …, 2022 - National Acad Sciences
Capturing mitochondria's intricate and dynamic structure poses a daunting challenge for
optical nanoscopy. Different labeling strategies have been demonstrated for live-cell …

Super-resolution structured illumination microscopy

R Heintzmann, T Huser - Chemical reviews, 2017 - ACS Publications
Super-resolved structured illumination microscopy (SR-SIM) is among the most rapidly
growing fluorescence microscopy techniques that can surpass the optical diffraction limit …

Faster, sharper, and deeper: structured illumination microscopy for biological imaging

Y Wu, H Shroff - Nature methods, 2018 - nature.com
Structured illumination microscopy (SIM) allows rapid, super-resolution (SR) imaging in live
specimens. We review recent technical advances in SR-SIM, with emphasis on imaging …

Three-dimensional structured illumination microscopy with enhanced axial resolution

X Li, Y Wu, Y Su, I Rey-Suarez, C Matthaeus… - Nature …, 2023 - nature.com
The axial resolution of three-dimensional structured illumination microscopy (3D SIM) is
limited to∼ 300 nm. Here we present two distinct, complementary methods to improve axial …