[HTML][HTML] Circular RNAs: Characterization, cellular roles, and applications

CX Liu, LL Chen - Cell, 2022 - cell.com
Most circular RNAs are produced from the back-splicing of exons of precursor mRNAs.
Recent technological advances have in part overcome problems with their circular …

[HTML][HTML] Metazoan micrornas

DP Bartel - Cell, 2018 - cell.com
MicroRNAs (miRNAs) are∼ 22 nt RNAs that direct posttranscriptional repression of mRNA
targets in diverse eukaryotic lineages. In humans and other mammals, these small RNAs …

Structure of the human DICER–pre-miRNA complex in a dicing state

YY Lee, H Lee, H Kim, VN Kim, SH Roh - Nature, 2023 - nature.com
Dicer has a key role in small RNA biogenesis, processing double-stranded RNAs
(dsRNAs),. Human DICER (hDICER, also known as DICER1) is specialized for cleaving …

Trends in the development of miRNA bioinformatics tools

L Chen, L Heikkinen, C Wang, Y Yang… - Briefings in …, 2019 - academic.oup.com
MicroRNAs (miRNAs) are small noncoding RNAs that regulate gene expression via
recognition of cognate sequences and interference of transcriptional, translational or …

miRNA biogenesis and regulation of diseases: an updated overview

A Vishnoi, S Rani - MicroRNA Profiling: Methods and Protocols, 2022 - Springer
MicroRNAs (miRNAs) are small RNA molecules, with their role in gene silencing and
translational repression by binding to the target mRNAs. Since it was discovered in 1993 …

MiRNA biogenesis and regulation of diseases: an overview

A Vishnoi, S Rani - MicroRNA profiling: Methods and protocols, 2017 - Springer
MicroRNAs (miRNAs) are small RNA molecules, with their role in gene silencing and
translational repression by binding to target mRNAs. Since it was discovered in 1993 …

The 'how'and 'where'of plant micro RNA s

Y Yu, T Jia, X Chen - New Phytologist, 2017 - Wiley Online Library
Micro RNA s (mi RNA s) are small non‐coding RNA s, of typically 20–24 nt, that regulate
gene expression post‐transcriptionally through sequence complementarity. Since the …

RNA-mediated epigenetic regulation of gene expression

D Holoch, D Moazed - Nature Reviews Genetics, 2015 - nature.com
Diverse classes of RNA, ranging from small to long non-coding RNAs, have emerged as key
regulators of gene expression, genome stability and defence against foreign genetic …

Metal nanoclusters: novel probes for diagnostic and therapeutic applications

Y Tao, M Li, J Ren, X Qu - Chemical Society Reviews, 2015 - pubs.rsc.org
Metal nanoclusters, composed of several to a few hundred metal atoms, have received
worldwide attention due to their extraordinary physical and chemical characteristics …

Natural RNA circles function as efficient microRNA sponges

TB Hansen, TI Jensen, BH Clausen, JB Bramsen… - Nature, 2013 - nature.com
MicroRNAs (miRNAs) are important post-transcriptional regulators of gene expression that
act by direct base pairing to target sites within untranslated regions of messenger RNAs …