[HTML][HTML] Roles and mechanisms of exosomal non-coding RNAs in human health and diseases

C Li, YQ Ni, H Xu, QY Xiang, Y Zhao, JK Zhan… - Signal transduction and …, 2021 - nature.com
Exosomes play a role as mediators of cell-to-cell communication, thus exhibiting pleiotropic
activities to homeostasis regulation. Exosomal non-coding RNAs (ncRNAs), mainly …

[HTML][HTML] Exosomes: key players in cancer and potential therapeutic strategy

J Dai, Y Su, S Zhong, L Cong, B Liu, J Yang… - Signal transduction and …, 2020 - nature.com
Exosomes are extracellular vesicles secreted by most eukaryotic cells and participate in
intercellular communication. The components of exosomes, including proteins, DNA, mRNA …

[HTML][HTML] Exosomes: Small vesicles with big roles in cancer, vaccine development, and therapeutics

A Thakur, DC Parra, P Motallebnejad, M Brocchi… - Bioactive materials, 2022 - Elsevier
Cancer is a deadly disease that is globally and consistently one of the leading causes of
mortality every year. Despite the availability of chemotherapy, radiotherapy, immunotherapy …

Cancer‐associated fibroblasts in breast cancer: Challenges and opportunities

D Hu, Z Li, B Zheng, X Lin, Y Pan, P Gong… - Cancer …, 2022 - Wiley Online Library
The tumor microenvironment is proposed to contribute substantially to the progression of
cancers, including breast cancer. Cancer‐associated fibroblasts (CAFs) are the most …

[HTML][HTML] The hypoxic tumour microenvironment

V Petrova, M Annicchiarico-Petruzzelli, G Melino… - Oncogenesis, 2018 - nature.com
Cancer progression often benefits from the selective conditions present in the tumour
microenvironment, such as the presence of cancer-associated fibroblasts (CAFs) …

[HTML][HTML] Extracellular vesicles-mediated intercellular communication: roles in the tumor microenvironment and anti-cancer drug resistance

S Maacha, AA Bhat, L Jimenez, A Raza, M Haris… - Molecular cancer, 2019 - Springer
The tumor microenvironment represents a complex network, in which tumor cells not only
communicate with each other but also with stromal and immune cells. Current research has …

[HTML][HTML] The role of Exosomal miRNAs in cancer

C Li, T Zhou, J Chen, R Li, H Chen, S Luo… - Journal of translational …, 2022 - Springer
Exosomal miRNAs have attracted much attention due to their critical role in regulating genes
and the altered expression of miRNAs in virtually all cancers affecting humans (Sun et al. in …

[HTML][HTML] Extracellular vesicles remodel tumor environment for cancer immunotherapy

M Yue, S Hu, H Sun, B Tuo, B Jia, C Chen, W Wang… - Molecular Cancer, 2023 - Springer
Tumor immunotherapy has transformed neoplastic disease management, yet low response
rates and immune complications persist as major challenges. Extracellular vesicles …

Cancer metabolism and tumor microenvironment: fostering each other?

Y Yuan, H Li, W Pu, L Chen, D Guo, H Jiang… - Science China Life …, 2022 - Springer
The changes associated with malignancy are not only in cancer cells but also in
environment in which cancer cells live. Metabolic reprogramming supports tumor cell high …

Exosomes in cancer development and clinical applications

YL Tai, KC Chen, JT Hsieh, TL Shen - Cancer science, 2018 - Wiley Online Library
Exosomes participate in cancer progression and metastasis by transferring bioactive
molecules between cancer and various cells in the local and distant microenvironments …