Emerging roles of glycopeptide antibiotics: Moving beyond gram-positive bacteria
Glycopeptides, a class of cell wall biosynthesis inhibitors, have been the antibiotics of choice
against drug-resistant Gram-positive bacterial infections. Their unique mechanism of action …
against drug-resistant Gram-positive bacterial infections. Their unique mechanism of action …
Emerging antiviral strategies to interfere with influenza virus entry
E Vanderlinden, L Naesens - Medicinal research reviews, 2014 - Wiley Online Library
Influenza A and B viruses are highly contagious respiratory pathogens with a considerable
medical and socioeconomical burden and known pandemic potential. Current influenza …
medical and socioeconomical burden and known pandemic potential. Current influenza …
Novel inhibitors of influenza virus fusion: structure-activity relationship and interaction with the viral hemagglutinin
E Vanderlinden, F Göktaş, Z Cesur… - Journal of …, 2010 - Am Soc Microbiol
ABSTRACT A new class of N-(1-thia-4-azaspiro [4.5] decan-4-yl) carboxamide inhibitors of
influenza virus hemagglutinin (HA)-mediated membrane fusion that has a narrow and …
influenza virus hemagglutinin (HA)-mediated membrane fusion that has a narrow and …
Analysis of carbohydrates and glycoconjugates by matrix‐assisted laser desorption/ionization mass spectrometry: An update for 2009–2010
DJ Harvey - Mass spectrometry reviews, 2015 - Wiley Online Library
This review is the sixth update of the original article published in 1999 on the application of
MALDI mass spectrometry to the analysis of carbohydrates and glycoconjugates and brings …
MALDI mass spectrometry to the analysis of carbohydrates and glycoconjugates and brings …
Recent advances in the synthesis of new glycopeptide antibiotics
PA Ashford, SP Bew - Chemical Society Reviews, 2012 - pubs.rsc.org
The vancomycin family of glycopeptide antibiotics has been inspiring research in the field of
synthetic chemistry since the 1980s. Recent studies have moved away from the focus of total …
synthetic chemistry since the 1980s. Recent studies have moved away from the focus of total …
Synthesis and antiviral properties of novel indole-based thiosemicarbazides and 4-thiazolidinones
G Cihan-Üstündağ, E Gürsoy, L Naesens… - Bioorganic & Medicinal …, 2016 - Elsevier
A novel series of indolylthiosemicarbazides (6a–6g) and their cyclization products, 4-
thiazolidinones (7a–7g), have been designed, synthesized and evaluated, in vitro, for their …
thiazolidinones (7a–7g), have been designed, synthesized and evaluated, in vitro, for their …
Synthesis, molecular modeling and antiviral activity of novel 5-fluoro-1H-indole-2, 3-dione 3-thiosemicarbazones
In this work, novel 5-fluoro-1-methyl/ethyl-1H-indole-2, 3-dione 3-[4-(substituted phenyl)-
thiosemicarbazones] 6a-n and 7a-n were synthesized. The antiviral effects of the …
thiosemicarbazones] 6a-n and 7a-n were synthesized. The antiviral effects of the …
Highlights in antiviral drug research: antivirals at the horizon
ED Clercq - Medicinal Research Reviews, 2013 - Wiley Online Library
This review highlights ten “hot topics” in current antiviral research:(i) new nucleoside
derivatives (ie, PSI‐352938) showing high potential as a direct antiviral against hepatitis C …
derivatives (ie, PSI‐352938) showing high potential as a direct antiviral against hepatitis C …
Influenza virus entry via the GM3 ganglioside-mediated platelet-derived growth factor receptor β signalling pathway
P Vrijens, S Noppen, T Boogaerts… - Journal of General …, 2019 - microbiologyresearch.org
The possible resistance of influenza virus against existing antiviral drugs calls for new
therapeutic concepts. One appealing strategy is to inhibit virus entry, in particular at the …
therapeutic concepts. One appealing strategy is to inhibit virus entry, in particular at the …
Semisynthetic teicoplanin derivatives with dual antimicrobial activity against SARS-CoV-2 and multiresistant bacteria
I Bereczki, V Vimberg, E Lőrincz, H Papp, L Nagy… - Scientific reports, 2022 - nature.com
Patients infected with SARS-CoV-2 risk co-infection with Gram-positive bacteria, which
severely affects their prognosis. Antimicrobial drugs with dual antiviral and antibacterial …
severely affects their prognosis. Antimicrobial drugs with dual antiviral and antibacterial …