Using deep learning to study emotional behavior in rodent models
JY Kuo, AJ Denman, NJ Beacher… - Frontiers in Behavioral …, 2022 - frontiersin.org
Quantifying emotional aspects of animal behavior (eg, anxiety, social interactions, reward,
and stress responses) is a major focus of neuroscience research. Because manual scoring …
and stress responses) is a major focus of neuroscience research. Because manual scoring …
The role of opioid transmission in music‐induced pleasure
Studies conducted in rodents indicate a crucial role of the opioid circuit in mediating
objective hedonic reactions to primary rewards. However, it remains unclear whether opioid …
objective hedonic reactions to primary rewards. However, it remains unclear whether opioid …
Beauty and uncertainty as transformative factors: a free energy principle account of aesthetic diagnosis and intervention in Gestalt psychotherapy
Drawing from field theory, Gestalt therapy conceives psychological suffering and
psychotherapy as two intentional field phenomena, where unprocessed and chaotic …
psychotherapy as two intentional field phenomena, where unprocessed and chaotic …
The Brain Salience Network at the Intersection of Pain and Substance use Disorders: Insights from Functional Neuroimaging Research
Abstract Purpose of Review The brain's salience network (SN), primarily comprising the
anterior insula and anterior cingulate cortex, plays a key role in detecting salient stimuli and …
anterior insula and anterior cingulate cortex, plays a key role in detecting salient stimuli and …
Drug repurposing candidates to treat core symptoms in autism spectrum disorder
E Koch, D Demontis - Frontiers in Pharmacology, 2022 - frontiersin.org
Autism spectrum disorder (ASD) is characterized by high heritability and clinical
heterogeneity. The main core symptoms are social communication deficits. There are no …
heterogeneity. The main core symptoms are social communication deficits. There are no …
Differential methylation of OPRK1 in borderline personality disorder is associated with childhood trauma
According to a growing body of neurobiological evidence, the core symptoms of borderline
personality disorder (BPD) may be linked to an opioidergic imbalance between the hedonic …
personality disorder (BPD) may be linked to an opioidergic imbalance between the hedonic …
Mu-opioid receptor system modulates responses to vocal bonding and distress signals in humans
L Sun, L Lukkarinen, V Putkinen… - … of the Royal …, 2022 - royalsocietypublishing.org
Laughter is a contagious prosocial signal that conveys bonding motivation; adult crying
conversely communicates desire for social proximity by signalling distress. Endogenous mu …
conversely communicates desire for social proximity by signalling distress. Endogenous mu …
A history of childhood maltreatment has substance-and sex-specific effects on craving during treatment for substance use disorders
S Gerhardt, K Eidenmueller, S Hoffmann… - Frontiers in …, 2022 - frontiersin.org
Rationale Childhood maltreatment (CM) leads to detrimental mental health outcomes, such
as substance use disorders (SUD). This study examined prevalence and severity of all five …
as substance use disorders (SUD). This study examined prevalence and severity of all five …
Intracerebroventricular injection of sclerostin reduced social hierarchy and impaired neuronal dendritic complexity in mice
W Li, Y Zhang, Y Su, Y Hao, X Wang, X Yin, M Gong… - Neuroscience …, 2022 - Elsevier
An increasing number of studies have demonstrated extensive functional links between
bone and the brain. As a novel endocrine organ, bone has received increasing attention for …
bone and the brain. As a novel endocrine organ, bone has received increasing attention for …
Morphine exposure during adolescence induces enduring social changes dependent on adolescent stage of exposure, sex, and social test.
DN King'uyu, EL Edgar, C Figueroa… - Behavioral …, 2023 - psycnet.apa.org
Drug exposure during adolescence, when the “reward” circuitry of the brain is developing,
can permanently impact reward-related behavior into adulthood. Epidemiological studies …
can permanently impact reward-related behavior into adulthood. Epidemiological studies …