The development of animal embryos is initially directed by maternal gene products. Then,
during the maternal-to-zygotic transition (MZT), developmental control is handed to the …

The origin story and emergence of molecular biology is muddled. The early triumphs in
bacterial genetics and the complexity of animal and plant genomes complicate an intricate …

A fertilized egg is initially transcriptionally silent and relies on maternally provided factors to
initiate development. For embryonic development to proceed, the oocyte-inherited …

Sex-specific splicing is an essential process that regulates sex determination and drives
sexual dimorphism. Yet, how early in development widespread sex-specific transcript …

Most Drosophila transposable elements are LTR retrotransposons, some of which belong to
the genus Errantivirus and share structural and functional characteristics with vertebrate …

The evolution of sex chromosomes, and patterns of sex-biased gene expression and
dosage compensation, are poorly known among early winged insects such as odonates. We …

Coenzyme A (CoA) is essential for metabolism and protein acetylation. Current knowledge
holds that each cell obtains CoA exclusively through biosynthesis via the canonical five-step …

Developmental gene regulatory networks (GRNs) underpin metazoan embryogenesis and
have undergone substantial modification to generate the tremendous variety of animal forms …

Background Maternal genes have a pivotal role in regulating metazoan early development.
As such their functions have been extensively studied since the dawn of developmental …

Metazoans exhibit two modes of primordial germ cell (PGC) specification that are
interspersed across taxa. However, the evolutionary link between the two modes and the …