[HTML][HTML] Tropane alkaloids: chemistry, pharmacology, biosynthesis and production

KL Kohnen-Johannsen, O Kayser - Molecules, 2019 - mdpi.com
Tropane alkaloids (TA) are valuable secondary plant metabolites which are mostly found in
high concentrations in the Solanaceae and Erythroxylaceae families. The TAs, which are …

Production of plant secondary metabolites: a historical perspective

F Bourgaud, A Gravot, S Milesi, E Gontier - Plant science, 2001 - Elsevier
Studies on plant secondary metabolites have been increasing over the last 50 years. These
molecules are known to play a major role in the adaptation of plants to their environment, but …

'Radicle'biochemistry: the biology of root-specific metabolism

HE Flores, JM Vivanco, VM Loyola-Vargas - Trends in plant science, 1999 - cell.com
The roots of higher plants are a fascinating and largely unexplored biological frontier. One of
their features is the ability to synthesize a remarkable diversity of secondary metabolites …

Ethnopharmacology, phytochemistry, and biotechnological advances of family Apocynaceae: A review

BS Bhadane, MP Patil, VL Maheshwari… - Phytotherapy …, 2018 - Wiley Online Library
The family Apocynaceae is one of the largest and important families in angiosperm. Several
members of this family have medicinal properties and have been in the treatment of various …

[HTML][HTML] Hairy root culture: a potent method for improved secondary metabolite production of Solanaceous plants

D Biswas, A Chakraborty, S Mukherjee… - Frontiers in Plant …, 2023 - frontiersin.org
Secondary metabolites synthesized by the Solanaceous plants are of major therapeutic and
pharmaceutical importance, many of which are commonly obtained from the roots of these …

[HTML][HTML] Exploring the metabolic stability of engineered hairy roots after 16 years maintenance

ST Häkkinen, E Moyano, RM Cusidó… - Frontiers in Plant …, 2016 - frontiersin.org
Plants remain a major source of new drugs, leads and fine chemicals. Cell cultures deriving
from plants offer a fascinating tool to study plant metabolic pathways and offer large scale …

The effect of nitrate and ammonium concentrations on growth and alkaloid accumulation of Atropa belladonna hairy roots

L Bensaddek, F Gillet, JEN Saucedo… - Journal of biotechnology, 2001 - Elsevier
The growth, the alkaloid production, as well as the scopolamine/hyoscyamine ratio of two
clones of belladonna hairy roots were studied. The effects of nitrate and ammonium …

Scopolamine: a journey from the field to clinics

SF Ullrich, H Hagels, O Kayser - Phytochemistry Reviews, 2017 - Springer
Tropane alkaloids are present in many different plants of the Solanaceae family and widely
known for their anticholinergic properties. Among them, most valued and increasingly …

Ethephon-induced changes in antioxidants and phenolic compounds in anthocyanin-producing black carrot hairy root cultures

G Barba-Espín, ST Chen, S Agnolet… - Journal of …, 2020 - academic.oup.com
Hairy root (HR) cultures are quickly evolving as a fundamental research tool and as a bio-
based production system for secondary metabolites. In this study, an efficient protocol for …

Improvement of Ornamental Characters and Fragrance Production in Lemon-scented Geranium Through Genetic Transformation by Agrobacterium rhizogenes

A Pellegrineschi, JP Damon, N Valtorta, N Paillard… - Bio/technology, 1994 - nature.com
We obtained transformed root cultures for the scented,“lemon geranium (Pelargonium sp.)
by inoculating stem and leaf fragments with Agrobacterium rhizogenes. Shoots regenerated …