Quantification and mapping of DNA modifications
Apart from the four canonical nucleobases, DNA molecules carry a number of natural
modifications. Substantial evidence shows that DNA modifications can regulate diverse …
modifications. Substantial evidence shows that DNA modifications can regulate diverse …
[HTML][HTML] Methods for Detection and Mapping of Methylated and Hydroxymethylated Cytosine in DNA
The chemical modifications of DNA are of pivotal importance in the epigenetic regulation of
cellular processes. Although the function of 5-methylcytosine (5mC) has been extensively …
cellular processes. Although the function of 5-methylcytosine (5mC) has been extensively …
Single-molecule quantification of 5-hydroxymethylcytosine for diagnosis of blood and colon cancers
Background The DNA modification 5-hydroxymethylcytosine (5hmC) is now referred to as
the sixth base of DNA with evidence of tissue-specific patterns and correlation with gene …
the sixth base of DNA with evidence of tissue-specific patterns and correlation with gene …
Quantification of global DNA hydroxymethylation level using UHRF2 SRA-luciferase based on bioluminescence resonance energy transfer
N Taka, S Asami, M Sakamoto, T Matsui… - Analytical …, 2022 - ACS Publications
5-Methylcytosine (5mC) plays an important role in the regulation of gene expression. Ten-
eleven translocation (TET) continuously oxidizes 5mC to 5-hydroxymethylcytosine (5hmC), 5 …
eleven translocation (TET) continuously oxidizes 5mC to 5-hydroxymethylcytosine (5hmC), 5 …
Hypersensitive quantification of global 5-hydroxymethylcytosine by chemoenzymatic tagging
hydroxymethylcytosine (5hmC) is an epigenetic DNA modification. Tissue-specific reduction
in global 5hmC levels has been associated with various types of cancer. One of the …
in global 5hmC levels has been associated with various types of cancer. One of the …
Dual-monomer solvatochromic probe system (DSPS) for effectively differentiating lipid raft cholesterol and active membrane cholesterol in the inner-leaflet plasma …
X Luo, Y Zhao, Y Cai, J Chen, L Zhao, T Lan… - Journal of Materials …, 2024 - pubs.rsc.org
Monitoring active membrane cholesterol and lipid raft cholesterol in the inner leaflet of the
plasma membrane is significant for understanding the membrane function and cellular …
plasma membrane is significant for understanding the membrane function and cellular …
[HTML][HTML] Cell-Free DNA Hydroxymethylation in Cancer: Current and Emerging Detection Methods and Clinical Applications
In the era of precision oncology, identifying abnormal genetic and epigenetic alterations has
transformed the way cancer is diagnosed, managed, and treated. 5-hydroxymethylcytosine …
transformed the way cancer is diagnosed, managed, and treated. 5-hydroxymethylcytosine …
Quantitation and mapping of the epigenetic marker 5‐hydroxymethylcytosine
We here review primary methods used in quantifying and mapping 5‐hydroxymethylcytosine
(5hmC), including global quantification, restriction enzyme‐based detection, and methods …
(5hmC), including global quantification, restriction enzyme‐based detection, and methods …
Irys extract
R Arielly, Y Ebenstein - Bioinformatics, 2018 - academic.oup.com
Irys Extract is a software tool for generating genomic information from data collected by the
BioNano Genomics Irys platform. The tool allows the user easy access to the raw data in the …
BioNano Genomics Irys platform. The tool allows the user easy access to the raw data in the …
[PDF][PDF] Chemical biology
J Bai, F Guo, M Li, Y Li, X Lei - 2021 - pdfs.semanticscholar.org
We here describe a fluorescent signal amplification method termed ''Click-based
amplification''that can be well integrated with various click-labelling modes, including …
amplification''that can be well integrated with various click-labelling modes, including …