RNA interference (RNAi) has become the method of choice to suppress gene expression in
vitro. It is also emerging as a powerful tool for in vivo research with over 90 studies …

The world raced to develop vaccines to protect against the rapid spread of SARS-CoV-2
infection upon the recognition of COVID-19 as a global pandemic. A broad spectrum of …

Liposome-based drug and gene delivery systems have potential for significant roles in a
variety of therapeutic applications. Recently, liposomes have been used to entrap gas and …

Skin cancer has always been and remains the leader among all tumors in terms of
occurrence. One of the main factors responsible for skin cancer, natural and artificial UV …

Synthetic oligodeoxynucleotides (ODN) containing CpG sequences are recognized as a
“danger” signal by the immune system of mammals. As a consequence, CpG ODN stimulate …

The purpose of this study was to investigate the molecular and therapeutic effects of siRNA-
mediated c-MYC silencing in cisplatin-resistant ovarian cancer. Statistical analysis of …

The potent Myc oncoprotein plays a pivotal role as a regulator of tumorigenesis in numerous
human cancers of diverse origin. Experimental evidence shows that inhibiting Myc …

The universal deregulation of c-myc gene expression in tumor cells suggests that this
oncogene represents an attractive target for cancer therapeutic purposes. The same applies …

Immunostimulatory oligodeoxynucleotides (ODN) containing cytosine-guanine (CpG) motifs
are powerful stimulators of innate as well as adaptive immune responses, exerting their …

Multilamellar vesicles (MLVs) are formed by the aqueous hydration of dried lipid films.
Typically hundreds of nanometers in diameter, they are large, complex structures containing …