Current challenges and best-practice protocols for microbiome analysis
Analyzing the microbiome of diverse species and environments using next-generation
sequencing techniques has significantly enhanced our understanding on metabolic …
sequencing techniques has significantly enhanced our understanding on metabolic …
Advances and challenges in metatranscriptomic analysis
Sequencing-based analyses of microbiomes have traditionally focused on addressing the
question of community membership and profiling taxonomic abundance through amplicon …
question of community membership and profiling taxonomic abundance through amplicon …
The human tumor microbiome is composed of tumor type–specific intracellular bacteria
Bacteria were first detected in human tumors more than 100 years ago, but the
characterization of the tumor microbiome has remained challenging because of its low …
characterization of the tumor microbiome has remained challenging because of its low …
The gut microbiome modulates the protective association between a Mediterranean diet and cardiometabolic disease risk
To address how the microbiome might modify the interaction between diet and
cardiometabolic health, we analyzed longitudinal microbiome data from 307 male …
cardiometabolic health, we analyzed longitudinal microbiome data from 307 male …
Species-level functional profiling of metagenomes and metatranscriptomes
Functional profiles of microbial communities are typically generated using comprehensive
metagenomic or metatranscriptomic sequence read searches, which are time-consuming …
metagenomic or metatranscriptomic sequence read searches, which are time-consuming …
PICRUSt2: An improved and extensible approach for metagenome inference
One major limitation of microbial community marker gene sequencing is that it does not
provide direct information on the functional composition of sampled communities. Here, we …
provide direct information on the functional composition of sampled communities. Here, we …
Dynamics of metatranscription in the inflammatory bowel disease gut microbiome
Inflammatory bowel disease (IBD) is a group of chronic diseases of the digestive tract that
affects millions of people worldwide. Genetic, environmental and microbial factors have …
affects millions of people worldwide. Genetic, environmental and microbial factors have …
Circulating levels of the short-chain fatty acid acetate mediate the effect of the gut microbiome on visceral fat
Background Acetate is a short-chain fatty acid (SCFA) produced by gut bacteria, which has
been implicated in cardio-metabolic health. Here we examine the relationships of circulating …
been implicated in cardio-metabolic health. Here we examine the relationships of circulating …
Exploring the human microbiome: the potential future role of next-generation sequencing in disease diagnosis and treatment
The interaction between the human microbiome and immune system has an effect on
several human metabolic functions and impacts our well-being. Additionally, the interaction …
several human metabolic functions and impacts our well-being. Additionally, the interaction …
Metagenomic approaches in microbial ecology: an update on whole-genome and marker gene sequencing analyses
AE Pérez-Cobas, L Gomez-Valero… - Microbial …, 2020 - microbiologyresearch.org
Metagenomics and marker gene approaches, coupled with high-throughput sequencing
technologies, have revolutionized the field of microbial ecology. Metagenomics is a culture …
technologies, have revolutionized the field of microbial ecology. Metagenomics is a culture …