Proliferating cell nuclear antigen (PCNA) plays critical roles in many aspects of DNA
replication and replication-associated processes, including translesion synthesis, error-free …

Proliferating cell nuclear antigen (PCNA) has a central role in promoting faithful DNA
replication, providing a molecular platform that facilitates the myriad protein–protein and …

The structure of the E. coli β clamp polymerase processivity factor has been solved in
complex with primed DNA. Interestingly, the clamp directly binds the DNA duplex and also …

Three-dimensional structures of DNA N-glycosylases and N-glycosylase/apyrimidine/
apurine (AP)-lyase enzymes and other critical components of base excision repair (BER) …

DNA mismatch repair (MMR) corrects non-Watson-Crick basepairs generated by replication
errors, recombination intermediates, and some forms of chemical damage to DNA. In MutS …

The sliding clamp proteins are present in almost all forms of life and participate in various
fundamental processes. Many of these proteins accommodate a conserved sequence that …

Modifications of the eukaryotic sliding clamp, proliferating cell nuclear antigen (PCNA), by
ubiquitin and the ubiquitin-related protein SUMO, are well known to influence the choice of …

From bacteria to mammals, DNA mismatch repair (MMR) pathway plays an essential role in
eliminating mismatched nucleotides and insertion-deletion mismatches during the process …

The proliferating cell nuclear antigen (PCNA) protein serves as a molecular platform
recruiting and coordinating the activity of factors involved in multiple deoxyribonucleic acid …

Sliding clamps encircle DNA and tether polymerases and other factors to the genomic
template. However, the molecular mechanism of clamp sliding on DNA is unknown. Using …