High-resolution computed tomography for clinical imaging of bone microarchitecture

AJ Burghardt, TM Link, S Majumdar - Clinical Orthopaedics and …, 2011 - journals.lww.com
Background The role of bone structure, one component of bone quality, has emerged as a
contributor to bone strength. The application of high-resolution imaging in evaluating bone …

Cortical bone porosity: what is it, why is it important, and how can we detect it?

DML Cooper, CE Kawalilak, K Harrison… - Current osteoporosis …, 2016 - Springer
There is growing recognition of the role of micro-architecture in osteoporotic bone loss and
fragility. This trend has been driven by advances in imaging technology, which have …

[图书][B] Microcomputed tomography: methodology and applications

SR Stock - 2019 - taylorfrancis.com
MicroComputed Tomography has become the gold standard for studying 3D microscopic
structures nondestructively, and this book provides up-to-date coverage of the modality. The …

[HTML][HTML] Old age causes de novo intracortical bone remodeling and porosity in mice

M Piemontese, M Almeida, AG Robling, HN Kim… - JCI insight, 2017 - ncbi.nlm.nih.gov
Decreased cortical thickness and increased cortical porosity are the key anatomic changes
responsible for osteoporotic fractures in elderly women and men. The cellular basis of these …

Age-dependent change in the 3D structure of cortical porosity at the human femoral midshaft

DML Cooper, CDL Thomas, JG Clement, AL Turinsky… - Bone, 2007 - Elsevier
Microstructural change associated with cortical bone remodeling has been extensively
explored with 2D techniques. However, relatively little is known regarding the 3D dynamic …

The relation of femoral osteon geometry to age, sex, height and weight

HM Britz, CDL Thomas, JG Clement, DML Cooper - Bone, 2009 - Elsevier
As computational modeling becomes an increasingly common tool for probing the regulation
of bone remodeling, the need for experimental data to refine and validate such models also …

Change in porosity is the major determinant of the variation of cortical bone elasticity at the millimeter scale in aged women

M Granke, Q Grimal, A Saïed, P Nauleau, F Peyrin… - Bone, 2011 - Elsevier
At the mesoscale (ie over a few millimeters), cortical bone can be described as two-phase
composite material consisting of pores and a dense mineralized matrix. The cortical porosity …

Micro-and nano-CT for the study of bone ultrastructure

F Peyrin, P Dong, A Pacureanu, M Langer - Current osteoporosis reports, 2014 - Springer
Micro-computed tomography (micro-CT)—a version of X-ray CT operating at high spatial
resolution—has had a considerable success for the investigation of trabecular bone micro …

[图书][B] Bone histology: an anthropological perspective

C Crowder, S Stout - 2011 - books.google.com
A broad understanding of bone and tooth microstructure is necessary for constructing the
biological profile of an individual or individuals within a population. Bone Histology: An …

Mathematical modeling of spatio‐temporal dynamics of a single bone multicellular unit

MD Ryser, N Nigam… - Journal of bone and …, 2009 - academic.oup.com
During bone remodeling, bone‐resorbing osteoclasts and bone‐forming osteoblasts are
organized in bone multicellular units (BMUs), which travel at a rate of 20–40 μm/d for 6–12 …