Polymeric in situ forming depots for long-acting drug delivery systems

AK Pandya, LK Vora, C Umeyor, D Surve… - Advanced Drug Delivery …, 2023 - Elsevier
Polymeric in situ forming depots have emerged as highly promising drug delivery systems
for long-acting applications. Their effectiveness is attributed to essential characteristics such …

Carbohydrate polymer-based bioadhesive formulations and their potentials for the treatment of ocular diseases: a review

X Tang, J Liu, R Yan, Q Peng - International Journal of Biological …, 2023 - Elsevier
Eyes are directly exposed to the outer environment and susceptible to infections, leading to
various ocular disorders. Local medication is preferred to treat eye diseases due to its …

Lipid-based nanocarriers for ocular drug delivery: An updated review

B Das, AK Nayak, S Mallick - Journal of Drug Delivery Science and …, 2022 - Elsevier
Recent years have witnessed a boom in ocular nanomedicine research with a number of
lipid-based nanocarriers such as liposomes, niosomes, cubosomes, nanoemulsions, solid …

Enhancement of ocular anti-glaucomic activity of agomelatine through fabrication of hyaluronic acid modified-elastosomes: formulation, statistical optimisation, in vitro …

AA Nemr, GM El-Mahrouk, HA Badie - Journal of …, 2023 - Taylor & Francis
Aim The aim of this manuscript was to fabricate agomelatine (AGM) loaded elastosomes to
improve its corneal permeation and ocular bioavailability. AGM is a biopharmaceutical …

Salutary influence of gemifloxacin mesylate nanocubosomes based-in situ ocular gel as a novel approach for the management of experimental keratitis induced by …

GA El-Emam, A Motawea, WE Abd El Hady… - Journal of Drug Delivery …, 2023 - Elsevier
In the era of Methicillin-resistant Staphylococcus aureus (MRSA) resulting in the
ineffectiveness of antibiotics is of keen interest to researchers in up-to-date scenarios. The …

Calcitermin-Loaded Smart Gels Activity against Candida albicans: A Preliminary In Vitro Study

D Bellotti, M D'accolti, W Pula, N Huang, F Simeliere… - Gels, 2023 - mdpi.com
Calcitermin is an antimicrobial peptide of 15 amino acids found in human nasal fluid
characterized by antifungal and antibacterial properties. Candida albicans is the most …

Nanotechnology-based fungal detection and treatment: current status and future perspective

V Chaudhari, V Vairagade, A Thakkar… - Naunyn-Schmiedeberg's …, 2024 - Springer
Fungal infections impose a significant impact on global health and encompass major
expenditures in medical treatments. Human mycoses, a fungal co-infection associated with …

Carbon Nanotube Hybrid Materials: Efficient and Pertinent Platforms for Antifungal Drug Delivery

DK Chandra, RL Reis, SC Kundu… - Advanced Materials …, 2023 - Wiley Online Library
Carbon nanotubes (CNTs) have emerged as the brightest nascent artifact to deliver
antifungal drugs in drug delivery applications, health care, and pharmaceutical industries …

Dynamic ex vivo porcine eye model to measure ophthalmic drug penetration under simulated lacrimal flow

GN Barbalho, MA Falcão, JMS Lopes, JM Lopes… - Pharmaceutics, 2023 - mdpi.com
Animal models are still used in the research and development of ophthalmic drug products,
mainly due to the difficulty in simulating natural physiological conditions with in vitro models …

[HTML][HTML] Blending Induced Variations in Poloxamer's/Pluronic's® Gelation: Thermodynamic and Rheological Perspectives

M Qutub, A Tatode, T Premchandani, J Taksande… - JCIS Open, 2024 - Elsevier
Amphiphilic block copolymers (ABCs) are currently significant in pharmaceutical sciences
because of their specific capability to develop various structures that are highly efficient for …