Parkinson's disease and parkinsonism
MT Hayes - The American journal of medicine, 2019 - Elsevier
Parkinson's disease is a progressive neurodegenerative disease characterized by tremor
and bradykinesia and is a common neurologic ailment. Male sex and advancing age are …
and bradykinesia and is a common neurologic ailment. Male sex and advancing age are …
[HTML][HTML] Autonomic dysfunction in Parkinson's disease: Implications for pathophysiology, diagnosis, and treatment
Z Chen, G Li, J Liu - Neurobiology of disease, 2020 - Elsevier
Parkinson's disease (PD) is a neurodegenerative disease with a 200 year-long research
history. Our understanding about its clinical phenotype and pathogenesis remains limited …
history. Our understanding about its clinical phenotype and pathogenesis remains limited …
Stool consistency is strongly associated with gut microbiota richness and composition, enterotypes and bacterial growth rates
Objective The assessment of potentially confounding factors affecting colon microbiota
composition is essential to the identification of robust microbiome based disease markers …
composition is essential to the identification of robust microbiome based disease markers …
Gastrointestinal dysfunction in Parkinson's disease
Our understanding of dysfunction of the gastrointestinal system in patients with Parkinson's
disease has increased substantially in the past decade. The entire gastrointestinal tract is …
disease has increased substantially in the past decade. The entire gastrointestinal tract is …
Neurodegenerative and neurodevelopmental diseases and the gut-brain axis: The potential of therapeutic targeting of the microbiome
The human gut microbiome contains the largest number of bacteria in the body and has the
potential to greatly influence metabolism, not only locally but also systemically. There is an …
potential to greatly influence metabolism, not only locally but also systemically. There is an …
Pathogenesis of Parkinson disease—the gut–brain axis and environmental factors
L Klingelhoefer, H Reichmann - Nature Reviews Neurology, 2015 - nature.com
Parkinson disease (PD) follows a defined clinical pattern, and a range of nonmotor
symptoms precede the motor phase. The predominant early nonmotor manifestations are …
symptoms precede the motor phase. The predominant early nonmotor manifestations are …
Alpha‐synuclein as a biomarker for Parkinson's disease
A Atik, T Stewart, J Zhang - Brain pathology, 2016 - Wiley Online Library
Parkinson's disease (PD) is a common neurodegenerative disorder, characterized
pathologically by the presence of α‐synuclein (α‐syn)‐rich Lewy bodies. As clinical …
pathologically by the presence of α‐synuclein (α‐syn)‐rich Lewy bodies. As clinical …
[HTML][HTML] The gut-brain axis in Parkinson's disease: possibilities for food-based therapies
P Perez-Pardo, T Kliest, HB Dodiya… - European journal of …, 2017 - Elsevier
Parkinson's disease (PD) is usually characterized by cardinal motor impairments. However,
a range of non-motor symptoms precede the motor-phase and are major determinants for …
a range of non-motor symptoms precede the motor-phase and are major determinants for …
Colonic biopsies to assess the neuropathology of Parkinson's disease and its relationship with symptoms
T Lebouvier, M Neunlist, S Bruley des Varannes… - PloS one, 2010 - journals.plos.org
Background The presence of Lewy bodies and Lewy neurites (LN) has been demonstrated
in the enteric nervous system (ENS) of Parkinson's disease (PD) patients. The aims of the …
in the enteric nervous system (ENS) of Parkinson's disease (PD) patients. The aims of the …
Evaluation of fecal microbiota transplantation in Parkinson's disease patients with constipation
X Kuai, X Yao, L Xu, Y Zhou, L Zhang, Y Liu, S Pei… - Microbial Cell …, 2021 - Springer
Parkinson's disease (PD) is a neurodegenerative disorder and 70–80% of PD patients suffer
from gastrointestinal dysfunction such as constipation. We aimed to assess the efficacy and …
from gastrointestinal dysfunction such as constipation. We aimed to assess the efficacy and …