Neural cell cycle dysregulation and central nervous system diseases
W Wang, B Bu, M Xie, M Zhang, Z Yu, D Tao - Progress in neurobiology, 2009 - Elsevier
The cell cycle is a delicately manipulated process essential for the development,
differentiation, proliferation and death of cells. Inappropriate activation of cell cycle …
differentiation, proliferation and death of cells. Inappropriate activation of cell cycle …
Protective role of anticancer drugs in neurodegenerative disorders: A drug repurposing approach
The disease heterogeneity and little therapeutic progress in neurodegenerative diseases
justify the need for novel and effective drug discovery approaches. Drug repurposing is an …
justify the need for novel and effective drug discovery approaches. Drug repurposing is an …
Identification of novel trophoblast invasion-related genes: heme oxygenase-1 controls motility via peroxisome proliferator-activated receptor γ
M Bilban, P Haslinger, J Prast, F Klinglmüller… - …, 2009 - academic.oup.com
Invasion of cytotrophoblasts (CTBs) into uterine tissues is essential for placental
development. To identify molecules regulating trophoblast invasion, mRNA signatures of …
development. To identify molecules regulating trophoblast invasion, mRNA signatures of …
ALS-linked SOD1 mutants enhance neurite outgrowth and branching in adult motor neurons
Amyotrophic lateral sclerosis (ALS) is a progressive, fatal neurodegenerative disease
characterized by motor neuron cell death. However, not all motor neurons are equally …
characterized by motor neuron cell death. However, not all motor neurons are equally …
Nutritional and exercise-based interventions in the treatment of amyotrophic lateral sclerosis
BP Patel, MJ Hamadeh - Clinical Nutrition, 2009 - Elsevier
BACKGROUND & AIMS: Disease pathogenesis in amyotrophic lateral sclerosis (ALS)
involves a number of interconnected mechanisms all resulting in the rapid deterioration of …
involves a number of interconnected mechanisms all resulting in the rapid deterioration of …
Mitochondrial involvement in amyotrophic lateral sclerosis: trigger or target?
SR Bacman, WG Bradley, CT Moraes - Molecular Neurobiology, 2006 - Springer
Despite numerous reports demonstrating mitochondrial abnormalities associated with
amyotrophic lateral sclerosis (ALS), the role of mitochondrial dysfunction in the disease …
amyotrophic lateral sclerosis (ALS), the role of mitochondrial dysfunction in the disease …
Proteins that bind to misfolded mutant superoxide dismutase-1 in spinal cords from transgenic amyotrophic lateral sclerosis (ALS) model mice
P Zetterström, KS Graffmo, PM Andersen… - Journal of Biological …, 2011 - ASBMB
Mutant superoxide dismutase-1 (SOD1) has an unidentified toxic property that provokes
ALS. Several ALS-linked SOD1 mutations cause long C-terminal truncations, which …
ALS. Several ALS-linked SOD1 mutations cause long C-terminal truncations, which …
Biochemical and molecular analyses of copper–zinc superoxide dismutase from a C4 plant Pennisetum glaucum reveals an adaptive role in response to oxidative …
S Mahanty, T Kaul, P Pandey, RA Reddy… - Gene, 2012 - Elsevier
Superoxide dismutases (SODs) form the foremost line of defense against ROS in aerobes.
Pennisetum glaucum cDNA library is constructed to isolate superoxide dismutase cDNA …
Pennisetum glaucum cDNA library is constructed to isolate superoxide dismutase cDNA …
Using ALS to understand profilin 1's diverse roles in cellular physiology
Profilin is an actin monomer‐binding protein whose role in actin polymerization has been
studied for nearly 50 years. While its principal biochemical features are now well …
studied for nearly 50 years. While its principal biochemical features are now well …
G93A SOD1 alters cell cycle in a cellular model of Amyotrophic Lateral Sclerosis
E Cova, A Ghiroldi, S Guareschi, G Mazzini… - Cellular signalling, 2010 - Elsevier
Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative multifactorial disease
characterized, like other diseases such as Alzheimer's disease (AD), Parkinson's disease …
characterized, like other diseases such as Alzheimer's disease (AD), Parkinson's disease …