Background The positive influences of glucagon-like peptide-1 (GLP-1) on blood glucose
homeostasis, appetite sensations, and food intake provide a strong rationale for its …

Over the last decade, a subfamily of G protein-coupled receptors that are agonized by
endogenous and dietary free-fatty acids (FFA) has been discovered. These free-fatty acid …

The G-protein coupled receptors (GPCRs) activated by free fatty acids (FFAs) have emerged
as new and exciting drug targets, due to their plausible translation from pharmacology to …

The dietary role of macronutrients and their metabolites in cancer has been evident for many
decades. Dietary ingestion of fat, carbohydrates, protein, and fiber, as well as probiotics that …

The incidence of noncommunicable diseases (NCDs) has increased over the last few
decades, and one of the major contributors to this is lifestyle, especially diet. High intake of …

Abstract Family of Free Fatty Acid Receptors (FFARs), specific G protein-coupled receptors
comprises of four members: FFAR1-4, where each responds to different chain length of fatty …

Crohn's disease (CD) is an inflammatory bowel disease (IBD) which is characterized by
chronic and relapsing inflammation of the gastrointestinal (GI) tract. The etiology of CD is …

Diabetic nephropathy (DN) is one of the most common causes of end-stage renal disease
worldwide. ω3-Fatty acids (ω3FAs) were found to attenuate kidney inflammation …

Fatty acid metabolism contributes to energy supply and plays an important role in regulating
immunity. Free fatty acids (FFAs) bind to free fatty acid receptors (FFARs) on the cell surface …

This study was carried out to determine the effects of flaxseed oil administration on gene
expression levels related to insulin, lipid and inflammation in overweight diabetic patients …