Objective To review the basic scientific status of repair in articular cartilage tissue and to
assess the efficiency of current clinical therapies instigated for the treatment of structural …

The ankle joint is subjected to more weight-bearing force per square centimeter and is more
commonly injured than any other joint in the body, but the prevalence of symptomatic …

The extracellular matrix (ECM) has long been regarded as a packing material; supporting
cells within the tissue and providing tensile strength and protection from mechanical stress …

This review assesses the evidence for the efficacy of therapies used in the management of
osteoarthritis in dogs on the basis of papers published in peerreviewed journals in English …

Objective Osteoarthritis (OA) is one of the most prevalent and disabling chronic conditions
affecting the elderly. Its etiology is largely unknown, but age is the most prominent risk factor …

Intervertebral disc degeneration describes the vicious cycle of the deterioration of
intervertebral discs and can eventually result in degenerative disc disease (DDD), which is …

In this Review we describe three approaches for cartilage tissue repair at the rheumatology–
orthopaedics interface: disease-modifying osteoarthritis (OA) drug (DMOAD) treatment; cell …

Objective Osteoarthritis (OA) is a degenerative, disabling joint disease that affects> 10% of
the adult population. No effective disease‐modifying treatment is available. In the present …

Objective Histomorphometric study on cartilage samples taken from osteoarthritic human
knees before and 6 months after intraarticular injections of a specific fraction (500–730kDa) …

Background This study evaluates changes in peri-articular bone in two canine models for
osteoarthritis: the groove model and the anterior cruciate ligament transection (ACLT) …