The pituitary gland controls many important physiological processes in vertebrates,
including growth, homeostasis, and reproduction. As in mammals, the teleost pituitary …

Kisspeptin, encoded by the KISS1 gene, was first discovered as a potential metastasis
suppressor gene. The prepro-kisspeptin precursor is cleaved into shorter mature bioactive …

The kiss1/gpr54 signaling system is considered to be a critical regulator of reproduction in
most vertebrates. However, this presumption has not been tested vigorously in …

Reproduction is essential for life, but its regulatory mechanism is diverse. The analysis of
this diversity should lead us to understand the evolutionary process of the regulation of …

Kisspeptin, a novel neuropeptide product of the Kiss1 gene, activates the G protein-coupled
membrane receptor G protein-coupled receptor 54 (now termed Kiss1r). Over the last 15 …

Reproduction is regulated by the hypothalamic-pituitary-gonadal (HPG) axis in vertebrates.
In addition to wealth of knowledge in mammals, recent studies in non-mammalian species …

This study, conducted in the brain of a perciform fish, the European sea bass, aimed at
raising antibodies against the precursor of the kisspeptins in order to map the kiss systems …

Neuropeptide kisspeptin has been suggested to be an essential central regulator of
reproduction in response to changes in serum gonadal steroid concentrations. However, in …

Kisspeptins are now considered key players in the neuroendocrine control of puberty and
reproduction, at least in mammals. Most teleosts have two kiss genes, kiss1 and kiss2, but …

Kisspeptins play a critical role in the control of hypothalamic-gonadotropic function and
puberty onset in mammals. Studies in fish have all supported the hypothesis that they might …