[HTML][HTML] Sex hormone fluctuation and increased female risk for depression and anxiety disorders: from clinical evidence to molecular mechanisms
M Kundakovic, D Rocks - Frontiers in neuroendocrinology, 2022 - Elsevier
Women are at twice the risk for anxiety and depression disorders as men are, although the
underlying biological factors and mechanisms are largely unknown. In this review, we …
underlying biological factors and mechanisms are largely unknown. In this review, we …
Effect of estrous cycle on behavior of females in rodent tests of anxiety
TA Lovick, H Zangrossi Jr - Frontiers in psychiatry, 2021 - frontiersin.org
Anxiety disorders are more prevalent in women than in men. In women the menstrual cycle
introduces another variable; indeed, some conditions eg, premenstrual syndrome, are …
introduces another variable; indeed, some conditions eg, premenstrual syndrome, are …
Sex differences in anxiety and emotional behavior
NC Donner, CA Lowry - Pflügers Archiv-European Journal of Physiology, 2013 - Springer
Research has elucidated causal links between stress exposure and the development of
anxiety disorders, but due to the limited use of female or sex-comparative animal models …
anxiety disorders, but due to the limited use of female or sex-comparative animal models …
Sex differences in animal models of psychiatric disorders
Psychiatric disorders are characterized by sex differences in their prevalence,
symptomatology and treatment response. Animal models have been widely employed for …
symptomatology and treatment response. Animal models have been widely employed for …
Epigenetic mechanisms underlying sex differences in the brain and behavior
M Kundakovic, M Tickerhoof - Trends in neurosciences, 2024 - cell.com
Sex differences are found across brain regions, behaviors, and brain diseases. Sexual
differentiation of the brain is initiated prenatally but it continues throughout life, as a result of …
differentiation of the brain is initiated prenatally but it continues throughout life, as a result of …
The stage of the estrus cycle is critical for interpretation of female mouse social interaction behavior
T Chari, S Griswold, NA Andrews… - Frontiers in behavioral …, 2020 - frontiersin.org
Female animals in biomedical research have traditionally been excluded from research
studies due to the perceived added complexity caused by the estrus cycle. However, given …
studies due to the perceived added complexity caused by the estrus cycle. However, given …
Relevance of stress and female sex hormones for emotion and cognition
JP Ter Horst, ER de Kloet, H Schächinger… - Cellular and molecular …, 2012 - Springer
There are clear sex differences in incidence and onset of stress-related and other psychiatric
disorders in humans. Yet, rodent models for psychiatric disorders are predominantly based …
disorders in humans. Yet, rodent models for psychiatric disorders are predominantly based …
Regulation of anxiety during the postpartum period
JS Lonstein - Frontiers in neuroendocrinology, 2007 - Elsevier
Healthy mother–infant interactions are critical for the physical, cognitive, and psychological
development of offspring. Such interactions rely on numerous factors, including a positive …
development of offspring. Such interactions rely on numerous factors, including a positive …
Hippocampus‐based behavioral, structural, and molecular dynamics across the estrous cycle
D Rocks, M Kundakovic - Journal of neuroendocrinology, 2023 - Wiley Online Library
The activity of neurons in the rodent hippocampus contributes to diverse behaviors, with the
activity of ventral hippocampal neurons affecting behaviors related to anxiety and emotion …
activity of ventral hippocampal neurons affecting behaviors related to anxiety and emotion …
Postnatal day 2 to 11 constitutes a 5-HT-sensitive period impacting adult mPFC function
TJ Rebello, Q Yu, NM Goodfellow… - Journal of …, 2014 - Soc Neuroscience
Early-life serotonin [5-hydroxytryptamine (5-HT)] signaling modulates brain development,
which impacts adult behavior, but 5-HT-sensitive periods, neural substrates, and behavioral …
which impacts adult behavior, but 5-HT-sensitive periods, neural substrates, and behavioral …