Oncolytic viruses have been taking the front stage in biological therapy for cancer recently.
The first and most potent virus to be used in oncolytic virotherapy is human adenovirus …

Newcastle disease virus (NDV) is an avian paramyxovirus, which has been demonstrated to
possess significant oncolytic activity against mammalian cancers. This review summarizes …

Intralesional therapy with oncolytic viruses (OVs) leads to the activation of local and systemic
immune pathways, which may present targets for further combinatorial therapies. Here, we …

Head and neck squamous cell carcinoma (HNSCC) have a high incidence and mortality
rate, and investigating the pathogenesis and potential therapeutic strategies of HNSCC is …

Oncolytic viruses are a relatively new class of anti-cancer immunotherapy agents. Several
viruses have undergone evaluation in clinical trials in the last decades, and the first agent is …

Oncolyic virotherapy is one of the modern experimental techniques to treat human cancers.
Here we studied the antitumor activity of wild-type Newcastle disease virus (NDV) isolates …

Oncolytic paramyxoviruses include some strains of Measles, Mumps, Newcastle disease,
and Sendai viruses. All these viruses are well equipped for promoting highly specific and …

The direct oncolytic effect of Newcastle disease virus (NDV) depends on the following two
aspects: the susceptibility of cancer cells to virus infection and the ability of virus itself to lyse …

Background Anaplastic thyroid cancer (ATC) is one of the most aggressive of all solid tumors
for which no effective therapies are currently available. Oncolytic Newcastle disease virus …

Preclinical studies demonstrate that a broad spectrum of human malignant cells can be
killed by oncolytic paramyxoviruses, which include cells of ecto-, endo-, and mesodermal …