Staphylococcus aureus infections: epidemiology, pathophysiology, clinical manifestations, and management

SYC Tong, JS Davis, E Eichenberger… - Clinical microbiology …, 2015 - Am Soc Microbiol
Staphylococcus aureus is a major human pathogen that causes a wide range of clinical
infections. It is a leading cause of bacteremia and infective endocarditis as well as …

Community-acquired pneumonia

DM Musher, AR Thorner - New England Journal of Medicine, 2014 - Mass Medical Soc
Community-Acquired Pneumonia | NEJM Skip to main content NEJM Group Follow Us
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Ceftazidime-avibactam versus meropenem in nosocomial pneumonia, including ventilator-associated pneumonia (REPROVE): a randomised, double-blind, phase 3 …

A Torres, N Zhong, J Pachl, JF Timsit… - The Lancet Infectious …, 2018 - thelancet.com
Background Nosocomial pneumonia is commonly associated with antimicrobial-resistant
Gram-negative pathogens. We aimed to assess the efficacy and safety of ceftazidime …

Efficacy of fifth generation cephalosporins against methicillin-resistant Staphylococcus aureus-A review

SR Selvan, D Ganapathy - Research Journal of Pharmacy and …, 2016 - indianjournals.com
In recent decades, microbial resistance has reached to an incredibly alarming levels,
leading to the development of more potent antimicrobial agents. MRSA (Methicillin-Resistant …

Evolving understanding of the causes of pneumonia in adults, with special attention to the role of pneumococcus

DM Musher, MS Abers, JG Bartlett - Clinical Infectious Diseases, 2017 - academic.oup.com
Before 1945, Streptococcus pneumoniae caused more than 90% of cases of pneumonia in
adults. After 1950, the proportion of pneumonia caused by pneumococcus began to decline …

A new GISc framework and competency set for curricula development at South African universities

H du Plessis, A Van Niekerk - South African Journal of Geomatics, 2014 - ajol.info
In this study the commonalities and inconsistencies between three Geographical Information
Science (GISc) competency sets are used to develop a new framework of essential …

Challenges in severe community-acquired pneumonia: a point-of-view review

A Torres, JD Chalmers, CS Dela Cruz… - Intensive care …, 2019 - Springer
Purpose Severe community-acquired pneumonia (SCAP) is still associated with substantial
morbidity and mortality. In this point-of-view review paper, a group of experts discuss the …

New antibiotics for bad bugs: where are we?

M Bassetti, M Merelli, C Temperoni… - Annals of clinical …, 2013 - Springer
Bacterial resistance to antibiotics is growing up day by day in both community and hospital
setting, with a significant impact on the mortality and morbidity rates and the financial burden …

Efficacy and safety of intravenous-to-oral lefamulin, a pleuromutilin antibiotic, for the treatment of community-acquired bacterial pneumonia: the phase III lefamulin …

TM File Jr, L Goldberg, A Das… - Clinical infectious …, 2019 - academic.oup.com
Background Lefamulin, a pleuromutilin antibiotic, is active against pathogens commonly
causing community-acquired bacterial pneumonia (CABP). The Lefamulin Evaluation …

Novel antibiotics for multidrug-resistant gram-positive microorganisms

D Koulenti, E Xu, I Yin Sum Mok, A Song… - Microorganisms, 2019 - mdpi.com
Increasing multidrug-resistance to Gram-positive pathogens, particularly to staphylococci,
enterococci and streptococci, is a major problem, resulting in significant morbidity, mortality …