The cardiac benefits of exercise have been recognized for centuries. Studies have
undisputedly shown that regular exercise is beneficial for the cardiovascular system in …

The benefits of exercise on the heart are well recognized, and clinical studies have
demonstrated that exercise is an intervention that can improve cardiac function in heart …

Heart failure (HF) is driven by the interplay between regulatory transcription factors and
dynamic alterations in chromatin structure. Pathologic gene transactivation in HF is …

Background: The development of heart failure (HF) remains a common complication
following an acute myocardial infarction (AMI), and is associated with substantial adverse …

High throughput sequencing technologies have become essential in studies on genomics,
epigenomics, and transcriptomics. Although sequencing information has traditionally been …

Despite current standard of care, the average 5-year mortality after an initial diagnosis of
heart failure (HF) is about 40%, reflecting an urgent need for new therapeutic approaches …

Abstract FOXM1 (Forkhead box M1) is a typical proliferation-associated transcription factor,
which stimulates cell proliferation and exhibits a proliferation-specific expression pattern …

RNA splicing represents a post-transcriptional mechanism to generate multiple functional
RNAs or proteins from a single transcript. The evolution of RNA splicing is a prime example …

Proteomics is a systems physiology discipline to address the large-scale characterization of
protein species within a biological system, be it a cell, a tissue, a body biofluid, an organism …

Among the chemokines discovered to date, nineteen are presently considered to be relevant
in heart disease and are involved in all stages of cardiovascular response to injury …