Significance: Oxidative stress is considered to be an important component of various
diseases. A vast number of methods have been developed and used in virtually all diseases …

Reactive oxygen species (ROS), which were originally characterized in terms of their
harmful effects on cells and invading microorganisms, are increasingly implicated in various …

Oxidative stress due to imbalance between ROS production and detoxification plays a
pivotal role in determining cell fate. In response to the excessive ROS, apoptotic signaling …

Glioblastomas (GBM) are the most common primary brain tumor with a median survival of 15
months. A population of cells with stem cell properties (glioblastoma stem cells, GSCs) …

Compelling evidence show that reactive oxygen species (ROS) levels are finely regulated in
the cell and can act as “second messengers” in response to diverse stimuli. In tumor …

Epithelial–mesenchymal transition (EMT) is recognized as a driving force of cancer cell
metastasis and drug resistance, two leading causes of cancer recurrence and cancer …

Abstract Aim Neutrophil extracellular traps (NETs) are mesh-like DNA fibers clad with
intracellular proteins that are cast out from neutrophils in response to certain stimuli. The …

Background The balance between oxidation and anti-oxidation is believed to be critical in
maintaining healthy biological systems. However, our endogenous antioxidant defense …

The carbon dioxide/bicarbonate (CO 2/HCO 3-) molecular pair is ubiquitous in mammalian
cells and tissues, mainly as a result of oxidative decarboxylation reactions that occur during …

The purpose of this review is to provide an overview of redox mechanisms, sources and
antioxidants that control signaling events in ECs. In particular, we describe which molecules …