Traumatic brain injury (TBI) causes brain damage, which involves primary and secondary
injury mechanisms. Primary injury causes local brain damage, while secondary damage …

Alzheimer's disease (AD) and Parkinson's disease (PD) are the most common
neurodegenerative diseases worldwide. They are characterized by the loss of neurons and …

Restoring function in chronic stages of spinal cord injury (SCI) has often been met with
failure or reduced efficacy when regenerative strategies are delayed past the acute or sub …

Armcx1 is highly expressed in the brain and is located in the mitochondrial outer membrane
of neurons, where it mediates mitochondrial transport. Mitochondrial transport promotes the …

Objective This study investigated the molecular mechanism of whether hUC-MSCs-EVs
repressed PTEN expression and activated the PI3K/AKT pathway through miR-29b-3p, thus …

Dulaglutide is a new type of hypoglycemic agent that agonizes glucagon-like peptide-1
receptor (GLP-1RA). It can be concluded from previous studies that a GLP-1RA can reduce …

Much research has focused on the PI3-kinase and PTEN signaling pathway with the aim to
stimulate repair of the injured central nervous system. Axons in the central nervous system …

Increased mTOR activity has been shown to enhance regeneration of injured axons by
increasing neuronal protein synthesis, while PTEN signaling can block mTOR activity to …

Patients who sustain a traumatic brain injury (TBI) are known to have a significantly quicker
fracture healing time than patients with isolated fractures, but the underlying mechanism has …

Recently, marked therapeutic effects pertaining to the recovery of injured rat spinal cords (1
min compression injury of the sacrocaudal spinal cord (S2-Co1) resulting in tail paralysis) …