Leptin, resistin and visfatin: the missing link between endocrine metabolic disorders and immunity

EA Al-Suhaimi, A Shehzad - European journal of medical research, 2013 - Springer
Adipose tissue is still regarded as a principle site for lipid storage and mobilizing tissue with
an important role in the control of energy homeostasis. Additionally, adipose tissue-secreted …

[HTML][HTML] AMPK: Lessons from transgenic and knockout animals

B Viollet, Y Athea, R Mounier, B Guigas… - Frontiers in …, 2009 - ncbi.nlm.nih.gov
AMP-activated protein kinase (AMPK), a phylogenetically conserved serine/threonine
protein kinase, has been proposed to function as a 'fuel gauge'to monitor cellular energy …

[PDF][PDF] Resistin and visfatin: regulators of insulin sensitivity, inflammation and immunity

A Stofkova - Endocr Regul, 2010 - researchgate.net
Adipokines play a significant role in the pathogenesis of a low-grade inflammation
associated with obesity and metabolic syndrome, and in chronic inflammatory and …

Molecular mechanisms underlying obesity-induced hypothalamic inflammation and insulin resistance: pivotal role of resistin/TLR4 pathways

Y Benomar, M Taouis - Frontiers in Endocrinology, 2019 - frontiersin.org
Low-grade inflammation and insulin resistance are among the clinical features of obesity
that are thought to promote the progressive onset of type 2 diabetes. However, the …

The brain and brown fat

C Contreras, F Gonzalez, J Fernø, C Diéguez… - Annals of …, 2015 - Taylor & Francis
Brown adipose tissue (BAT) is a specialized organ responsible for thermogenesis, a process
required for maintaining body temperature. BAT is regulated by the sympathetic nervous …

Central resistin overexposure induces insulin resistance through Toll-like receptor 4

Y Benomar, A Gertler, P De Lacy, D Crépin… - Diabetes, 2013 - Am Diabetes Assoc
Resistin promotes both inflammation and insulin resistance associated with energy
homeostasis impairment. However, the resistin receptor and the molecular mechanisms …

Resistin's, obesity and insulin resistance: the continuing disconnect between rodents and humans

X Huang, Z Yang - Journal of endocrinological investigation, 2016 - Springer
Purpose This review aimed to discuss the conflicting findings from resistin research in
rodents and humans as well as recent advances in our understanding of resistin's role in …

[HTML][HTML] When do we eat? Ingestive behavior, survival, and reproductive success

JE Schneider, JD Wise, NA Benton, JM Brozek… - Hormones and …, 2013 - Elsevier
The neuroendocrinology of ingestive behavior is a topic central to human health, particularly
in light of the prevalence of obesity, eating disorders, and diabetes. The study of food intake …

Role of resistin in insulin sensitivity in rodents and humans

KM Barnes, JL Miner - Current Protein and Peptide Science, 2009 - ingentaconnect.com
Resistin is a potential link between obesity and insulin resistance or type 2 diabetes. In
rodents, resistin is primarily expressed in and secreted from mature adipocytes, with some …

Changes in neurohormonal gut peptides following bariatric surgery

CN Ochner, C Gibson, M Shanik, V Goel… - International journal of …, 2011 - nature.com
The rising prevalence of obesity has reached pandemic proportions, with an associated cost
estimated at up to 7% of health expenditures worldwide. Bariatric surgery is currently the …