Diagnosing COVID-19: the disease and tools for detection

B Udugama, P Kadhiresan, HN Kozlowski… - ACS …, 2020 - ACS Publications
COVID-19 has spread globally since its discovery in Hubei province, China in December
2019. A combination of computed tomography imaging, whole genome sequencing, and …

Multiomic analysis of cytokines in immuno-oncology

V Jurisic - Expert review of proteomics, 2020 - Taylor & Francis
Introduction: Cytokines are a diverse group of peptides produced by different cell types
including cancer cells and various subpopulations of immune system cells. They exert their …

Cytokine levels in critically ill patients with COVID-19 and other conditions

M Kox, NJB Waalders, EJ Kooistra, J Gerretsen… - Jama, 2020 - jamanetwork.com
Methods| All patients in this study were admitted to the intensive care unit (ICU) of Radboud
University Medical Center. Plasma concentrations of the proinflammatory cytokines tumor …

Bioanalytical chemistry of cytokines–a review

JA Stenken, AJ Poschenrieder - Analytica chimica acta, 2015 - Elsevier
Cytokines are bioactive proteins produced by many different cells of the immune system.
Due to their role in different inflammatory disease states and maintaining homeostasis, there …

Elevated immune response in the brain of autistic patients

X Li, A Chauhan, AM Sheikh, S Patil, V Chauhan… - Journal of …, 2009 - Elsevier
This study determined immune activities in the brain of ASD patients and matched normal
subjects by examining cytokines in the brain tissue. Our results showed that proinflammatory …

Distinct cytokine patterns identified from multiplex profiles of murine DSS and TNBS-induced colitis

P Alex, NC Zachos, T Nguyen… - Inflammatory bowel …, 2009 - academic.oup.com
Background The cytokine network in inflammatory bowel disease (IBD) is a complex,
dynamic system that plays an important role in regulating mucosal innate and adaptive …

Cytokine profiles as markers of disease severity in sepsis: a multiplex analysis

FA Bozza, JI Salluh, AM Japiassu, M Soares, EF Assis… - Critical care, 2007 - Springer
Introduction The current shortage of accurate and readily available, validated biomarkers of
disease severity in sepsis is an important limitation when attempting to stratify patients into …

ELISA and multiplex technologies for cytokine measurement in inflammation and aging research

SX Leng, JE McElhaney, JD Walston… - The Journals of …, 2008 - academic.oup.com
Over the last decade there has been an enormous expansion of research focused on
defining the role of inflammation in aging, age-related diseases, disability, and frailty. The …

Prerequisites for cytokine measurements in clinical trials with multiplex immunoassays

W De Jager, K Bourcier, GT Rijkers, BJ Prakken… - BMC immunology, 2009 - Springer
Background Growing knowledge about cellular interactions in the immune system, including
the central role of cytokine networks, has lead to new treatments using monoclonal …

Conceptual and methodological issues relevant to cytokine and inflammatory marker measurements in clinical research

X Zhou, MS Fragala, JE McElhaney… - Current Opinion in …, 2010 - journals.lww.com
Conceptual and methodological issues relevant to cytokine an... : Current Opinion in
Clinical Nutrition & Metabolic Care Conceptual and methodological issues relevant to …