Paris saponin VII, a Hippo pathway activator, induces autophagy and exhibits therapeutic potential against human breast cancer cells

Y Xiang, P Peng, X Liu, X Jin, J Shen, T Zhang… - Acta Pharmacologica …, 2022 - nature.com
Dysregulation of the Hippo signaling pathway seen in many types of cancer is usually
associated with a poor prognosis. Paris saponin VII (PSVII) is a steroid saponin isolated from …

Sculponeatin A promotes the ETS1-SYVN1 interaction to induce SLC7A11/xCT-dependent ferroptosis in breast cancer

P Peng, Y Ren, F Wan, M Tan, H Wu, J Shen, C Qian… - Phytomedicine, 2023 - Elsevier
Abstract Background E26 transformation specificity-1 (ETS1) is a transcription factor that is
overexpressed in breast cancer (BC) and promotes tumor progression. Sculponeatin A (stA) …

G protein pathway suppressor 2 suppresses aerobic glycolysis through RACK1-mediated HIF-1α degradation in breast cancer

Y Si, H Ou, X Jin, M Gu, S Sheng, W Peng… - Free Radical Biology …, 2024 - Elsevier
Aerobic glycolysis has been recognized as a hallmark of human cancer. G protein pathway
suppressor 2 (GPS2) is a negative regulator of the G protein-MAPK pathway and a core …

[HTML][HTML] Breast cancer metastasis in sellar and suprasellar region. A rare presentation, and the ideal clinical management

T Holanda, IMF Pimentel… - Interdisciplinary …, 2024 - Elsevier
Background Breast cancer is the more common tumor in women. The first description date
1789 by Mr. Hughes described a case of breast cancer of a 44-year-old married woman. The …

[HTML][HTML] Case of incidental thoracic spinal dumbbell hemorrhagic arachnoid cyst and tentorial metastasis from breast carcinoma

G Scalia, R Costanzo, MP Silven… - Surgical Neurology …, 2023 - ncbi.nlm.nih.gov
Background: Spinal arachnoid cysts (SACs) in adults are typically acquired dural defects
following trauma, inflammation, or infection. Brain metastases from breast cancer account for …

[PDF][PDF] Brain Metastasis: Clinical and Biological Approach

V Sánchez-Martín - scibasejournals.org
Cancer includes a broad group of diseases that are characterized by the uncontrolled
growth of abnormal cells, which can affect any part of the organism, and according to the …