Vaccines are among the greatest inventions in medicine, leading to the elimination or
control of numerous diseases, including smallpox, polio, measles, rubella, and, most …

Abstract Development of an effective vaccine against the leading human bacterial pathogen
group A Streptococcus (GAS) is a public health priority. The species defining group A cell …

Pneumococcal infections cause serious illness and death among older adults. The capsular
polysaccharide vaccine PPSV23 and conjugated alternative PCV13 can prevent these …

The current opioid epidemic is one of the most profound public health crises facing the
United States. Despite that it has been under the spotlight for years, available treatments for …

Recent global events have drawn into focus the diversity of options for combatting disease
across a spectrum of prophylactic and therapeutic approaches. The recent success of the …

There is an unmet need for a stable and nonreactogenic vaccine against the bioterrorism
agent, Coxiella burnetii, causing Q fever. Here a safe, effective, and non‐reactogenic Q fever …

Abstract During 2020, the COVID-19 pandemic affected almost 10 8 individuals. Quite a
number of vaccines against COVID-19 were therefore developed, and a few recently …

This paper gives an overview of conjugate glycovaccines which contain recombinant
diphtheria toxoid CRM197 as a carrier protein. A special focus is given to synthetic methods …

Diseases caused by microbial bacteria such as Haemophilus influenzae type b (Hib),
Streptococcus pneumoniae and Neisseria meningitidis are still very serious disease, which …

Maintenance and regeneration of the zebrafish olfactory epithelium (OE) are supported by
two distinct progenitor cell populations that occupy spatially discrete stem cell niches and …