[HTML][HTML] Gut-liver axis, gut microbiota, and its modulation in the management of liver diseases: a review of the literature

I Milosevic, A Vujovic, A Barac, M Djelic… - International journal of …, 2019 - mdpi.com
The rapid scientific interest in gut microbiota (GM) has coincided with a global increase in
the prevalence of infectious and non-infectivous liver diseases. GM, which is also called “the …

Immune responses in the liver

P Kubes, C Jenne - Annual review of immunology, 2018 - annualreviews.org
The liver is a key, frontline immune tissue. Ideally positioned to detect pathogens entering
the body via the gut, the liver appears designed to detect, capture, and clear bacteria …

Ferroptosis in hepatocellular carcinoma: mechanisms and targeted therapy

A Ajoolabady, D Tang, G Kroemer, J Ren - British journal of cancer, 2023 - nature.com
Hepatocellular carcinoma is the most prevalent form of primary liver cancer with a
multifactorial aetiology comprising genetic, environmental, and behavioural factors. Evading …

Epidemiological and etiological variations in hepatocellular carcinoma

E Sagnelli, M Macera, A Russo, N Coppola, C Sagnelli - Infection, 2020 - Springer
Background Hepatocellular carcinoma (HCC) is the most prevalent form of liver cancer and
a leading cause of cancer-related deaths worldwide. The major risk factors for HCC …

Global epidemiology, prevention, and management of hepatocellular carcinoma

LY Mak, V Cruz-Ramón, P Chinchilla-López… - American Society of …, 2018 - ascopubs.org
The incidence rate of hepatocellular carcinoma (HCC) is rising. It is one of the most common
cancers worldwide and accounts for substantial morbidity and mortality. Chronic hepatitis B …

[HTML][HTML] Hepatokines and adipokines in NASH-related hepatocellular carcinoma

O Kucukoglu, JP Sowa, GD Mazzolini, WK Syn… - Journal of …, 2021 - Elsevier
The incidence of hepatocellular carcinoma (HCC) is increasing in industrialized societies;
this is likely secondary to the increasing burden of non-alcoholic fatty liver disease (NAFLD) …

[HTML][HTML] Biomarkers and subtypes of deranged lipid metabolism in non-alcoholic fatty liver disease

JM Mato, C Alonso, M Noureddin… - World journal of …, 2019 - ncbi.nlm.nih.gov
Nonalcoholic fatty liver disease (NAFLD) is a heterogeneous and complex disease that is
imprecisely diagnosed by liver biopsy. NAFLD covers a spectrum that ranges from simple …

[PDF][PDF] Diabetes medications and risk of HCC

MC Plaz Torres, A Jaffe, R Perry, E Marabotto… - …, 2022 - Wiley Online Library
Type 2 diabetes mellitus is a recognized risk factor for HCC in patients with liver disease,
independent from the etiology of their liver disease. Hence, prevention and treatment of type …

[HTML][HTML] Metabolic spectrum of liver failure in type 2 diabetes and obesity: from NAFLD to NASH to HCC

H Kim, DS Lee, TH An, HJ Park, WK Kim… - International journal of …, 2021 - mdpi.com
Liver disease is the spectrum of liver damage ranging from simple steatosis called as
nonalcoholic fatty liver disease (NAFLD) to hepatocellular carcinoma (HCC). Clinically …

MicroRNA-378 promotes hepatic inflammation and fibrosis via modulation of the NF-κB-TNFα pathway

T Zhang, J Hu, X Wang, X Zhao, Z Li, J Niu, CJ Steer… - Journal of …, 2019 - Elsevier
Background & Aims The progression of hepatosteatosis to non-alcoholic steatohepatitis
(NASH) is a critical step in the pathogenesis of hepatocellular cancer. However, the …