Coumarin derivatives as acetyl-and butyrylcholinestrase inhibitors: An in vitro, molecular docking, and molecular dynamics simulations study

MN Abu-Aisheh, A Al-Aboudi, MS Mustafa… - Heliyon, 2019 - cell.com
Alzheimer's disease is an irreversible and progressive brain disease that can cause
problems with memory and thinking skills. It is characterized by loss of cognitive ability and …

Synthesis, characterization, and bioactivity of new bisamidrazone derivatives as possible anticancer agents

MA Al-Qtaitat, MM El-Abadelah, DA Sabbah… - Medicinal Chemistry …, 2018 - Springer
A novel series of new di-(N-piperazin-1-yl) amidrazones and related congeners (3a–s) was
synthesized by reaction of Nʹ, Nʺ-(biphenyl-4, 4ʹ-diyl)-bis (2-oxopropanehydrazonoyl …

Synthesis, Characterization, and Bioactivity of Novel Bicinnolines Having 1‐Piperazinyl Moieties

MA Al‐Qtaitat, MM El‐Abadelah… - Journal of …, 2019 - Wiley Online Library
A number of novel bicinnolines containing piperazine moieties, 4a–o, were synthesized via
polyphosphoric acid‐catalyzed intramolecular cyclization of the respective acyl amidrazone …

Synthesis and Biological Activity of Some New N1-(4-oxoquinolin-6-yl) amidrazones

SA Musameh, SS Sabri… - Letters in Organic …, 2016 - ingentaconnect.com
Background: Oriented research towards discovery of new antimicrobial agents continues as
several microbes develop resistance to currently approved drugs. A selected set of N1-(1 …

Synthesis and Bioassay of Novel Substituted Pyrano[2,3‐f]cinnoline‐2‐ones

AS Al‐zagameem, MM El‐Abadelah… - Journal of …, 2016 - Wiley Online Library
A new series of 9‐substituted‐4, 10‐dimethylpyrano [2, 3‐f] cinnolin‐2‐ones (5a, 5b, 5c, 5d,
5e, 5f, 5g, 5h, 5i, 5j, 5k, 5l, 5m) were synthesized via intramolecular cyclization of the …

The Reactivity of Nitrile Imines

C Jamieson, K Livingstone, C Jamieson… - The Nitrile Imine 1, 3 …, 2020 - Springer
One of the most unique properties of nitrile imines in comparison to other 1, 3-dipoles is their
diverse reactivity profile with a number of distinct substrates. This chapter aims to categorise …

[PDF][PDF] Coumarin derivatives as acetyl-and butyrylcholinestrase inhibitors: An in vitro, molecular docking, and molecular dynamics

MN Abu-Aisheh, A Al-Aboudi, MS Mustafa, M Mustafa… - academia.edu
Alzheimer's disease is an irreversible and progressive brain disease that can cause
problems with memory and thinking skills. It is characterized by loss of cognitive ability and …

Bicyclic 5-6 Systems With One Bridgehead (Ring Junction) Nitrogen Atom: Two Extra Heteroatoms 0: 2

C Lalli - Comprehensive Heterocyclic Chemistry IV, 2022 - univ-rennes.hal.science
Reactivity of substituents attached to ring carbon atoms 9 8 Ring syntheses classified by
number of ring atoms in each component 12 8.1 Pyrrolo [1, 2-b][1, 2, 4] triazine 12 8.2 …