Gambling disorder (GD), previously called pathological gambling and classified as an
impulse control disorder in DSM‐III and DSM‐IV, has recently been reclassified as an …

Signalling reward delivery with sounds and lights is common practice in electronic games,
and may seem like a superficially harmless feature of game design. Such audiovisual cues …

Rationale Win-paired stimuli can promote risk taking in experimental gambling paradigms in
both rats and humans. We previously demonstrated that atomoxetine, a noradrenaline …

Rationale The flashing lights and sounds of modern casinos are alluring and may contribute
to the addictive nature of gambling. Such cues can have a profound impact on the …

Traumatic brain injury (TBI) affects 2.8 million people annually in the United States, with
significant populations suffering from ongoing cognitive dysfunction. Impairments in decision …

Rationale Pairing rewarding outcomes with audiovisual cues in simulated gambling games
increases risky choice in both humans and rats. However, the cognitive mechanism through …

Rationale Impairments in attention and inhibitory control are endophenotypic markers of
neuropsychiatric disorders such as schizophrenia and represent key targets for therapeutic …

Background Attention-deficit/hyperactivity disorder (ADHD) is associated with higher
substance use rates. Stimulant and non-stimulant pharmacotherapy improve adolescent …

Amphetamine (AMP) and atomoxetine (ATX) represent two of the most widely studied drug
treatments used in the investigation of impulsive behaviour. While both drugs have relatively …

Risky choice is associated with maladaptive behaviors, particularly substance use disorders.
Current animal models of risky choice are often confounded by other constructs like …