Global trends in hepatocellular carcinoma epidemiology: implications for screening, prevention and therapy

AG Singal, F Kanwal, JM Llovet - Nature reviews Clinical oncology, 2023 - nature.com
Hepatocellular carcinoma (HCC) mortality rates are increasing globally, and particularly in
the Western world. Cirrhosis remains the predominant risk factor for HCC. However …

[PDF][PDF] Emerging immunotherapy for HCC: A guide for hepatologists

F Foerster, SJ Gairing, SI Ilyas, PR Galle - Hepatology, 2022 - Wiley Online Library
HCC is one of the most common cancers worldwide, and the third leading cause of cancer‐
related death globally. HCC comprises nearly 90% of all cases of primary liver cancer …

NAFLD-driven HCC: Safety and efficacy of current and emerging treatment options

F Foerster, SJ Gairing, L Müller, PR Galle - Journal of hepatology, 2022 - Elsevier
In light of a global rise in obesity and type 2 diabetes, non-alcoholic fatty liver disease
(NAFLD) and non-alcoholic steatohepatitis (NASH) represent an increasingly important …

Trial design and endpoints in hepatocellular carcinoma: AASLD consensus conference

JM Llovet, A Villanueva, JA Marrero, M Schwartz… - …, 2021 - Wiley Online Library
Hepatocellular carcinoma (HCC) is the fourth leading cause of cancer-related mortality
worldwide.(1, 2) This neoplasm has some unique characteristics. It occurs in most cases …

EASL clinical practice guidelines: management of hepatocellular carcinoma

PR Galle, A Forner, JM Llovet, V Mazzaferro… - Journal of …, 2018 - Elsevier
Liver cancer is the fifth most common cancer and the second most frequent cause of cancer-
related death globally. Hepatocellular carcinoma represents about 90% of primary liver …

Goals and targets for personalized therapy for HCC

T Couri, A Pillai - Hepatology international, 2019 - Springer
Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related mortality
worldwide and its incidence continues to rise. While cirrhosis underlies most cases of HCC …

Prognostic and therapeutic implications of microvascular invasion in hepatocellular carcinoma

DJ Erstad, KK Tanabe - Annals of surgical oncology, 2019 - Springer
Hepatocellular carcinoma (HCC) is a morbid condition for which surgical and ablative
therapy are the only options for cure. Nonetheless, over half of patients treated with an R0 …

Evidence-based diagnosis, staging, and treatment of patients with hepatocellular carcinoma

J Bruix, M Reig, M Sherman - Gastroenterology, 2016 - Elsevier
Evidence-based management of patients with hepatocellular carcinoma (HCC) is key to
their optimal care. For individuals at risk for HCC, surveillance usually involves …

Hepatocellular carcinoma: clinical frontiers and perspectives

J Bruix, GJ Gores, V Mazzaferro - Gut, 2014 - gut.bmj.com
Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related death and is
currently the main event leading to death in patients with cirrhosis. Evolving information …

Hepatocellular carcinoma: from diagnosis to treatment

MS Grandhi, AK Kim, SM Ronnekleiv-Kelly, IR Kamel… - Surgical oncology, 2016 - Elsevier
Primary liver cancer is the sixth most common cancer overall and the second most common
cause of cancer mortality worldwide. Hepatocellular carcinoma accounts for up to 90% of all …