Neural mechanisms of stress resilience and vulnerability

TB Franklin, BJ Saab, IM Mansuy - Neuron, 2012 - cell.com
Exposure to stressful events can be differently perceived by individuals and can have
persistent sequelae depending on the level of stress resilience or vulnerability of each …

Tissue-specific actions of glucocorticoids on apoptosis: a double-edged sword

AL Gruver-Yates, JA Cidlowski - Cells, 2013 - mdpi.com
First described for their metabolic and immunosuppressive effects, glucocorticoids are
widely prescribed in clinical settings of inflammation. However, glucocorticoids are also …

Comparing adult hippocampal neurogenesis in mammalian species and orders: influence of chronological age and life history stage

I Amrein, K Isler, HP Lipp - European Journal of Neuroscience, 2011 - Wiley Online Library
Adult hippocampal neurogenesis is a prominent event in rodents. In species with longer life
expectancies, newly born cells in the adult dentate gyrus of the hippocampal formation are …

Disconnection and reconnection: the morphological basis of (mal) adaptation to stress

N Sousa, OFX Almeida - Trends in neurosciences, 2012 - cell.com
Maladaptive responses to stress and the associated hypersecretion of glucocorticoids cause
psychopathologies ranging from hyperemotional states and mood dysfunction to cognitive …

Stress, glucocorticoid hormones, and hippocampal neural progenitor cells: implications to mood disorders

T Kino - Frontiers in physiology, 2015 - frontiersin.org
The hypothalamic-pituitary-adrenal (HPA) axis and its end-effectors glucocorticoid
hormones play central roles in the adaptive response to numerous stressors that can be …

Adult neurogenesis under control of the circadian system

AAH Ali, C von Gall - Cells, 2022 - mdpi.com
The mammalian circadian system is a hierarchically organized system, which controls a 24-
h periodicity in a wide variety of body and brain functions and physiological processes …

HEI-OC1 cells as a model for investigating drug cytotoxicity

G Kalinec, P Thein, C Park, F Kalinec - Hearing research, 2016 - Elsevier
Abstract The House Ear Institute-Organ of Corti 1 (HEI-OC1) is one of the few, and arguable
the most used, mouse auditory cell line available for research purposes. Originally proposed …

Knockdown of the glucocorticoid receptor alters functional integration of newborn neurons in the adult hippocampus and impairs fear-motivated behavior

CP Fitzsimons, LWA Van Hooijdonk, M Schouten… - Molecular …, 2013 - nature.com
Glucocorticoids (GCs) secreted after stress reduce adult hippocampal neurogenesis, a
process that has been implicated in cognitive aspects of psychopathology, amongst others …

Maternity: neural mechanisms, motivational processes, and physiological adaptations.

M Numan, B Woodside - Behavioral neuroscience, 2010 - psycnet.apa.org
This review focuses on research on both the neural substrate of maternal responsiveness
and on the physiological, behavioral, and motivational adaptations to the maternal state. The …

Nongenomic glucocorticoid receptor action regulates gap junction intercellular communication and neural progenitor cell proliferation

RA Samarasinghe, R Di Maio… - Proceedings of the …, 2011 - National Acad Sciences
Glucocorticoids (GCs) are used to treat pregnant women at risk for preterm delivery;
however, prenatal exposure to GCs may trigger adverse neurological side effects due to …