Macrophages orchestrate airway inflammation, remodeling, and resolution in asthma

RD Britt Jr, A Ruwanpathirana, ML Ford… - International journal of …, 2023 - mdpi.com
Asthma is a heterogenous chronic inflammatory lung disease with endotypes that manifest
different immune system profiles, severity, and responses to current therapies. Regardless of …

The role of biodiversity in the development of asthma and allergic sensitization: a state-of-the-science review

I Paciência, N Sharma, TT Hugg… - Environmental …, 2024 - ehp.niehs.nih.gov
Background: Changes in land use and climate change have been reported to reduce
biodiversity of both the environment and human microbiota. These reductions in biodiversity …

Severe asthma and biological therapies: now and the future

O Sardon-Prado, C Diaz-Garcia… - Journal of Clinical …, 2023 - mdpi.com
Recognition of phenotypic variability in pediatric asthma allows for a more personalized
therapeutic approach. Knowledge of the underlying pathophysiological and molecular …

Involvement and repair of epithelial barrier dysfunction in allergic diseases

HF Lu, YC Zhou, LT Yang, Q Zhou, XJ Wang… - Frontiers in …, 2024 - frontiersin.org
The epithelial barrier serves as a critical defense mechanism separating the human body
from the external environment, fulfilling both physical and immune functions. This barrier …

Lung microbiome as a treatable trait in chronic respiratory disorders

F Scialò, M Vitale, V D'Agnano, DF Mariniello… - Lung, 2023 - Springer
Once thought to be a sterile environment, it is now established that lungs are populated by
various microorganisms that participate in maintaining lung function and play an important …

Cardiovascular changes under the microgravity environment and the gut microbiome

R Siddiqui, R Qaisar, K Al-Dahash, AH Altelly… - Life Sciences in Space …, 2024 - Elsevier
In view of the critical role the gut microbiome plays in human health, it has become clear that
astronauts' gut microbiota composition changes after spending time in space. Astronauts are …

The Impact of Oral Diseases on Respiratory Health and the Influence of Respiratory Infections on the Oral Microbiome

A Gupta, LM Saleena, P Kannan, A Shivachandran - Journal of Dentistry, 2024 - Elsevier
Objective The objective of this review is to examine the relationship between oral diseases
and respiratory health, investigating how oral microbiome disruptions contribute to …

Early prediction of asthma

SJ Romero-Tapia, JR Becerril-Negrete… - Journal of Clinical …, 2023 - mdpi.com
The clinical manifestations of asthma in children are highly variable, are associated with
different molecular and cellular mechanisms, and are characterized by common symptoms …

[PDF][PDF] Respiratory microbiome profiles are associated with distinct inflammatory phenotype and lung function in children with asthma

YH Kim, MR Park, SY Kim, MJ Kim, KW Kim… - J Investig Allergol Clin …, 2024 - jiaci.org
Background: Respiratory microbiome studies have improved our understanding of the
various phenotypes and endotypes in heterogeneous asthma. However, the relationship …

Daqing formula ameliorated allergic asthma and airway dysbacteriosis in mice challenged with ovalbumin and ampicillin

L Wu, QY Peng, XJ Li, MY Guo, JQ He, HZ Ying… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Asthma is a chronic airway inflammatory disease that can
lead to several complications caused by bacterial infections. However, recurrent attacks of …