All serious fungal infections need appropriate antifungal therapy for successful patient
outcome. Only a few classes of antifungal drugs are available, so the emergence of …

Fungi of the genus Aspergillus are widespread in the environment. Some Aspergillus
species, most commonly Aspergillus fumigatus, may lead to a variety of allergic reactions …

It is important to realize that guidelines cannot always account for individual variation among
patients. They are not intended to supplant physician judgment with respect to particular …

Abstract The European Society for Clinical Microbiology and Infectious Diseases, the
European Confederation of Medical Mycology and the European Respiratory Society Joint …

Invasive aspergillosis (IA) in haematology/oncology patients presents as primary infection or
breakthrough infection, which can become refractory to antifungal treatment and has a high …

In recent years, the global public health community has increasingly recognized the
importance of antimicrobial stewardship (AMS) in the fight to improve outcomes, decrease …

Invasive fungal infections constitute a serious threat to an ever-growing population of
immunocompromised individuals and other individuals at risk. Traditional diagnostic …

Breakthrough invasive fungal infections (IFI s) have emerged as a significant problem in
patients receiving systemic antifungals; however, consensus criteria for defining …

Hematopoietic stem cell transplantation is a highly specialized and unique medical
procedure. Autologous transplantation allows the administration of high-dose chemotherapy …

Antifungal prophylaxis can reduce morbidity and mortality from invasive fungal disease
(IFD). However, its use needs to be optimised and appropriately targeted to patients at …