[HTML][HTML] Biomarkers in chronic kidney disease: a review

RG Fassett, SK Venuthurupalli, GC Gobe… - Kidney international, 2011 - Elsevier
Chronic kidney disease (CKD) is a major public health problem. The classification of CKD by
KDOQI and KDIGO and the routine eGFR reporting have resulted in increased identification …

Established and emerging markers of kidney function

MA Ferguson, SS Waikar - Clinical chemistry, 2012 - academic.oup.com
BACKGROUND The kidney performs a multitude of essential functions to maintain
homeostasis. In clinical medicine, glomerular filtration rate (GFR) provides the best index of …

New potential biomarkers for chronic kidney disease management—A review of the literature

I Lousa, F Reis, I Beirão, R Alves, L Belo… - International Journal of …, 2020 - mdpi.com
The prevalence of chronic kidney disease (CKD) is increasing worldwide, and the mortality
rate continues to be unacceptably high. The biomarkers currently used in clinical practice …

Biomarkers of diabetic nephropathy: A 2017 update

N Papadopoulou-Marketou… - Critical reviews in …, 2017 - Taylor & Francis
Diabetic nephropathy (DN), also named diabetic kidney disease (DKD), is a devastating
complication in patients with both type 1 and 2 diabetes mellitus (T1D and T2D) and its …

GFR estimation using β-trace protein and β2-microglobulin in CKD

LA Inker, H Tighiouart, J Coresh, MC Foster… - American journal of …, 2016 - Elsevier
Background β-Trace protein (BTP) and β 2-microglobulin (B2M) are novel glomerular
filtration markers that have stronger associations with adverse outcomes than creatinine …

A new panel-estimated GFR, including β2-microglobulin and β-trace protein and not including race, developed in a diverse population

LA Inker, SJ Couture, H Tighiouart, AG Abraham… - American Journal of …, 2021 - Elsevier
Rationale and Objective Glomerular filtration rate (GFR) estimation based on creatinine and
cystatin C (eGFR cr-cys) is more accurate than estimated GFR (eGFR) based on creatinine …

Effect of kidney function on drug kinetics and dosing in neonates, infants, and children

F Rodieux, M Wilbaux, JN van den Anker… - Clinical …, 2015 - Springer
Neonates, infants, and children differ from adults in many aspects, not just in age, weight,
and body composition. Growth, maturation and environmental factors affect drug kinetics …

Novel markers of kidney function as predictors of ESRD, cardiovascular disease, and mortality in the general population

BC Astor, T Shafi, RC Hoogeveen, K Matsushita… - American journal of …, 2012 - Elsevier
BACKGROUND: Cystatin C level predicts mortality more strongly than serum creatinine
level. It is unknown whether this advantage extends to other outcomes, such as kidney …

A review of specific biomarkers of chronic renal injury and their potential application in nonclinical safety assessment studies

LA Obert, SA Elmore, D Ennulat… - Toxicologic …, 2021 - journals.sagepub.com
A host of novel renal biomarkers have been developed over the past few decades which
have enhanced monitoring of renal disease and drug-induced kidney injury in both …

Biomarkers in nephrology: core curriculum 2013

GM McMahon, SS Waikar - American Journal of Kidney Diseases, 2013 - ajkd.org
The clinical assessment and management of pa-tients with known or suspected kidney
disease has been aided for decades by biomarkers, a term defined by a National Institutes …