Photodynamic therapy (PDT) is a well-established treatment option in the treatment of
certain cancerous and pre-cancerous lesions. Though best-known for its application in …

Photodynamic inactivation (PDI) has been used to inactivate microorganisms through the
use of photosensitizers. The inactivation of mammalian viruses and bacteriophages by …

Photodynamic antimicrobial agents based on the well-established phenothiazinium
biological stain methylene blue offer a simple method for the inactivation or destruction of …

We present a review of the current status of the use of methylene blue (MB)
photoinactivation of viruses starting with the first early observations up to its current use to …

The virucidal properties of photoactive phenothiazine dyes, such as methylene blue, have
been known approximately 70 years. The mechanism of virus inactivation involves binding …

Lorna M. Williamson, Rebecca Cardigan, and Chi-is V Prowwse ith current donor-selection
criteria and virus genome testing, fresh-frozen plasma (FFP) in the developed world is …

ABSTRACT A series of four phenothiazine dyes, including methylene blue (MB), were
previously tested for their ability to photoinactivate viruses in red cell suspensions. One of …

Aim: Conventional disinfection techniques, considered safe for plasma, are usually
associated with collateral damages on concentrated platelets and erythrocytes. Alternative …

Inactivation of viruses in blood plasma can be achieved by photodynamic procedures using
methylene blue (MB) or other photoactive dyes. Singlet molecular oxygen (1O2) probably …

The few approved disinfection techniques for blood derivatives promote damage in the
blood components, representing risks for the transfusion receptor. Antimicrobial …