Environmental enrichment effects on the brain-derived neurotrophic factor expression in healthy condition, Alzheimer's disease, and other neurodegenerative …

D Cutuli, E Landolfo, L Petrosini… - Journal of Alzheimer's …, 2022 - content.iospress.com
Brain-derived neurotrophic factor (BDNF), a protein belonging to the neurotrophin family, is
known to be heavily involved in synaptic plasticity processes that support brain …

Exercise as an antidepressant: exploring its therapeutic potential

DJ Hwang, JH Koo, TK Kim, YC Jang, AH Hyun… - Frontiers in …, 2023 - frontiersin.org
The COVID-19 pandemic has increased the prevalence of depressive disorders worldwide,
requiring alternative treatments beyond medication and psychotherapy. Exercise has …

Gut microbiota depletion from early adolescence alters anxiety and depression-related behaviours in male mice with Alzheimer-like disease

B Mosaferi, Y Jand, AA Salari - Scientific Reports, 2021 - nature.com
The gut-microbiota–brain axis plays an important role in stress-related disorders, and
dysfunction of this complex bidirectional system is associated with Alzheimer's disease. This …

Anti-depressant-like effects of rannasangpei and its active ingredient crocin-1 on chronic unpredictable mild stress mice

Y Du, YL Wang, L Chen, QE Li, Y Cheng - Frontiers in Pharmacology, 2023 - frontiersin.org
Major depressive disorder is one of the most common neuropsychiatric diseases and it is a
global public health problem that leads to disabilities. Currently, there is a growing need to …

Voluntary physical activity increases maternal care and reduces anxiety-and depression-related behaviours during the postpartum period in mice

S Naghibi, A Barzegari, M Shariatzadeh, M Vatandoust… - Brain Research, 2022 - Elsevier
A growing body of evidence suggests voluntary physical activity is associated with
decreased stress-related disorders such as anxiety-and depression-like behaviours in both …

Exercise intensity and sex alter neurometabolic, transcriptional, and functional recovery following traumatic brain injury

BA White, JT Ivey, R Velazquez-Cruz, R Oliverio… - Experimental …, 2023 - Elsevier
Physical exercise represents a potentially inexpensive, accessible, and optimizable
rehabilitation approach to traumatic brain injury (TBI) recovery. However, little is known …

Swimming exercise strain-dependently affects maternal care and depression-related behaviors through gestational corticosterone and brain serotonin in postpartum …

F Ebrahimian, N Najdi, FF Masrour, AA Salari - Brain Research Bulletin, 2022 - Elsevier
Pregnancy is a very complex and highly stressful time in which women become more
physically and emotionally vulnerable. Therefore, mothers are more likely to face decreased …

Adolescent swimming exercise following maternal valproic acid treatment improves cognition and reduces stress-related symptoms in offspring mice: Role of sex and …

A Barzegari, HA Mahdirejei, M Hanani… - Physiology & …, 2023 - Elsevier
Valproic acid (VPA) treatment during pregnancy is a risk factor for developing autism
spectrum disorder, cognitive deficits, and stress-related disorders in children. No effective …

Asymmetric dysregulation of glutamate dynamics across the synaptic cleft in a mouse model of Alzheimer's disease

KJ Brymer, EP Hurley, JC Barron, B Mukherjee… - Acta Neuropathologica …, 2023 - Springer
Most research on glutamate spillover focuses on the deleterious consequences of
postsynaptic glutamate receptor overactivation. However, two decades ago, it was noted that …

Female rats are more responsive than are males to the protective effects of voluntary physical activity against the behavioral consequences of inescapable stress

MK Tanner, AA Hohorst, SM Mellert, EC Loetz… - Stress, 2023 - Taylor & Francis
Common stress-related mental health disorders affect women more than men. Physical
activity can provide protection against the development of future stress-related mental health …