Pathogenesis of lipid disorders in insulin resistance: a brief review

P Bjornstad, RH Eckel - Current diabetes reports, 2018 - Springer
Purpose of review Insulin resistance (IR) is recognized to play an important role in the
pathogenesis of dyslipidemia. This review summarizes the complex interplay between IR …

Comprehensive genetic study of the insulin resistance marker TG: HDL-C in the UK Biobank

A Oliveri, RJ Rebernick, A Kuppa, A Pant, Y Chen… - Nature …, 2024 - nature.com
Insulin resistance (IR) is a well-established risk factor for metabolic disease. The ratio of
triglycerides to high-density lipoprotein cholesterol (TG: HDL-C) is a surrogate marker of IR …

Early insulin resistance, type 2 diabetes, and treatment options in childhood

N Polidori, F Mainieri, F Chiarelli, A Mohn… - Hormone research in …, 2022 - karger.com
Abstract Background: Type 2 diabetes (T2D) represents just the tip of the iceberg of the
complex metabolic alterations associated with obesity and other clinical conditions …

Assessing the relationship between systemic immune-inflammation index and metabolic syndrome in children with obesity

DM Nicoară, AI Munteanu, AC Scutca, N Mang… - International Journal of …, 2023 - mdpi.com
Childhood obesity represents a worldwide concern as many countries have reported an
increase in its incidence, with possible cardiovascular long-term implications. The …

Association between non-insulin-based insulin resistance indices and cardiovascular events in patients undergoing percutaneous coronary intervention: a …

Z Zhang, L Zhao, Y Lu, X Meng, X Zhou - Cardiovascular Diabetology, 2023 - Springer
Background Insulin resistance (IR) has been confirmed that getting involved in the
pathophysiological process of cardiovascular diseases (CVD). Recently, increasing …

A non-invasive approach to identify insulin resistance with triglycerides and HDL-c ratio using machine learning

M Chakradar, A Aggarwal, X Cheng, A Rani… - Neural Processing …, 2023 - Springer
Identification and quantification of insulin resistance require specific blood test which is
complex, time-consuming, and much more invasive, making it difficult to track the changes …

The potential shared role of inflammation in insulin resistance and schizophrenia: a bidirectional two-sample mendelian randomization study

BI Perry, S Burgess, HJ Jones, S Zammit… - PLoS …, 2021 - journals.plos.org
Background Insulin resistance predisposes to cardiometabolic disorders, which are
commonly comorbid with schizophrenia and are key contributors to the significant excess …

Evaluation of TG-HDL ratio instead of HOMA ratio as insulin resistance marker in overweight and children with obesity

EG Behiry, NM El Nady, OM AbdEl Haie… - … Metabolic & Immune …, 2019 - ingentaconnect.com
Background: Homeostasis model assessment for insulin resistance (HOMA-IR) is widely
used as a marker of insulin resistance in adults and has also been validated in children and …

TG: HDL‐C Ratio Is a Good Marker to Identify Children Affected by Obesity with Increased Cardiometabolic Risk and Insulin Resistance

AK Nur Zati Iwani, MY Jalaludin… - International Journal …, 2019 - Wiley Online Library
Metabolic syndrome (MetS) is an important predictor of cardiovascular diseases in
adulthood. This study aims to examine the clinical utility of triglyceride to high‐density …

Triglycerides/high-density lipoprotein cholesterol is a predictor similar to the triglyceride–glucose index for the diagnosis of metabolic syndrome using International …

NNA Çin, H Yardımcı, N Koç, SA Uçaktürk… - Journal of Pediatric …, 2020 - degruyter.com
Objectives Metabolic syndrome (MS) is a fatal endocrinopathy that begins with insulin
resistance (IR) and causes abdominal obesity, glucose intolerance, or systemic disorders …