Getting the pain you expect: mechanisms of placebo, nocebo and reappraisal effects in humans

I Tracey - Nature medicine, 2010 - nature.com
The perception of pain is subject to powerful influences. Understanding how these are
mediated at a neuroanatomical and neurobiological level provides us with valuable …

Neurobiological mechanisms of the placebo effect

F Benedetti, HS Mayberg, TD Wager… - Journal of …, 2005 - Soc Neuroscience
1Department of Neuroscience, University of Turin Medical School, 10125 Turin, Italy,
2Department of Psychiatry and Behavioral Sciences, Emory University, Atlanta, Georgia …

Neuropharmacological dissection of placebo analgesia: expectation-activated opioid systems versus conditioning-activated specific subsystems

M Amanzio, F Benedetti - Journal of Neuroscience, 1999 - Soc Neuroscience
We investigated the mechanisms underlying the activation of endogenous opioids in
placebo analgesia by using the model of human experimental ischemic arm pain. Different …

Placebo and nocebo effects are defined by opposite opioid and dopaminergic responses

DJ Scott, CS Stohler, CM Egnatuk… - Archives of general …, 2008 - jamanetwork.com
Context Placebo and nocebo effects, the therapeutic and adverse effects, respectively, of
inert substances or sham procedures, represent serious confounds in the evaluation of …

Placebo analgesia and its opioidergic regulation suggest that empathy for pain is grounded in self pain

M Rütgen, EM Seidel, G Silani… - Proceedings of the …, 2015 - National Acad Sciences
Empathy for pain activates brain areas partially overlapping with those underpinning the first-
hand experience of pain. It remains unclear, however, whether such shared activations …

[HTML][HTML] Placebo and nocebo effects: the advantage of measuring expectations and psychological factors

N Corsi, L Colloca - Frontiers in psychology, 2017 - frontiersin.org
Several studies have explored the predictability of placebo and nocebo individual
responses by investigating personality factors and expectations of pain decreases and …

Predicting individual differences in placebo analgesia: contributions of brain activity during anticipation and pain experience

TD Wager, LY Atlas, LA Leotti… - Journal of …, 2011 - Soc Neuroscience
Recent studies have identified brain correlates of placebo analgesia, but none have
assessed how accurately patterns of brain activity can predict individual differences in …

[HTML][HTML] Individual differences in reward responding explain placebo-induced expectations and effects

DJ Scott, CS Stohler, CM Egnatuk, H Wang… - Neuron, 2007 - cell.com
Expectations, positive or negative, are modulating factors influencing behavior. They are
also thought to underlie placebo effects, impacting perceptions and biological processes …

Mind does really matter: Evidence from neuroimaging studies of emotional self-regulation, psychotherapy, and placebo effect

M Beauregard - Progress in neurobiology, 2007 - Elsevier
This article reviews neuroimaging studies of conscious and voluntary regulation of various
emotional states (sexual arousal, sadness, negative emotion). The results of these studies …

Neurobiological mechanisms of placebo responses

JK Zubieta, CS Stohler - Annals of the New York Academy of …, 2009 - Wiley Online Library
Expectations, positive or negative, are modulating factors influencing behavior. They are
also thought to underlie placebo effects, potentially impacting perceptions and biological …