Impaired adipose tissue function and insulin resistance remain instrumental in promoting
hepatic lipid accumulation in conditions of metabolic syndrome. In fact, enhanced lipid …

Nonalcoholic Fatty Liver Disease (NAFLD) is one of the most important causes of liver
disease worldwide and probably destined to become the leading cause of end‐stage liver …

Alcohol‐induced liver injury implicates inflammation and oxidative stress as important
mediators. Despite rigorous research, there is still no Food and Drug Administration (FDA) …

Objective (s): Metformin (Met), an antidiabetic biguanide, reduces hyperglycemia via
improving glucose utilization and reducing the gluconeogenesis. Met has been shown to …

The aim of the current study was to investigate the antioxidative effect of metformin (MTF) on
bile duct ligation (BDL)-induced hepatic disorder and histological damage in rats. The rats …

Gut microbiota is a crucial factor in pathogenesis of non-alcoholic steatohepatitis (NASH).
Therefore, targeting the gut–liver axis might be a novel therapeutic approach to treat NASH …

Non-alcoholic fatty liver disease (NAFLD) is a global public health problem that causes liver-
related morbidity and mortality. It is also an independent risk factor for non-communicable …

Silymarin and quercetin (SQ) are known antioxidants with substantial free radical
scavenging activities. The efficacy of SQ activity is restricted due to poor absorption and …

Non-alcoholic fatty liver disease (NAFLD) constitutes a major health problem worldwide and
intimately links with obesity and diabetes. This study aimed to explore the therapeutic impact …

The disruption of redox state homeostasis, the overexpression of lipogenic transcription
factors and enzymes, and the increase in lipogenic precursors induced by sweetened …