Computation through neural population dynamics

S Vyas, MD Golub, D Sussillo… - Annual review of …, 2020 - annualreviews.org
Significant experimental, computational, and theoretical work has identified rich structure
within the coordinated activity of interconnected neural populations. An emerging challenge …

The population doctrine in cognitive neuroscience

RB Ebitz, BY Hayden - Neuron, 2021 - cell.com
A major shift is happening within neurophysiology: a population doctrine is drawing level
with the single-neuron doctrine that has long dominated the field. Population-level ideas …

[HTML][HTML] Flexible multitask computation in recurrent networks utilizes shared dynamical motifs

LN Driscoll, K Shenoy, D Sussillo - Nature Neuroscience, 2024 - nature.com
Flexible computation is a hallmark of intelligent behavior. However, little is known about how
neural networks contextually reconfigure for different computations. In the present work, we …

Preserved neural dynamics across animals performing similar behaviour

M Safaie, JC Chang, J Park, LE Miller, JT Dudman… - Nature, 2023 - nature.com
Animals of the same species exhibit similar behaviours that are advantageously adapted to
their body and environment. These behaviours are shaped at the species level by selection …

Long-term stability of cortical population dynamics underlying consistent behavior

JA Gallego, MG Perich, RH Chowdhury, SA Solla… - Nature …, 2020 - nature.com
Animals readily execute learned behaviors in a consistent manner over long periods of time,
and yet no equally stable neural correlate has been demonstrated. How does the cortex …

[HTML][HTML] Vagus nerve stimulation drives selective circuit modulation through cholinergic reinforcement

S Bowles, J Hickman, X Peng, WR Williamson… - Neuron, 2022 - cell.com
Vagus nerve stimulation (VNS) is a neuromodulation therapy for a broad and expanding set
of neurologic conditions. However, the mechanism through which VNS influences central …

Robotic hand augmentation drives changes in neural body representation

P Kieliba, D Clode, RO Maimon-Mor, TR Makin - Science robotics, 2021 - science.org
Humans have long been fascinated by the opportunities afforded through augmentation.
This vision not only depends on technological innovations but also critically relies on our …

Stabilization of a brain–computer interface via the alignment of low-dimensional spaces of neural activity

AD Degenhart, WE Bishop, ER Oby… - Nature biomedical …, 2020 - nature.com
The instability of neural recordings can render clinical brain–computer interfaces (BCIs)
uncontrollable. Here, we show that the alignment of low-dimensional neural manifolds (low …

Cortical preparatory activity indexes learned motor memories

X Sun, DJ O'Shea, MD Golub, EM Trautmann, S Vyas… - Nature, 2022 - nature.com
The brain's remarkable ability to learn and execute various motor behaviours harnesses the
capacity of neural populations to generate a variety of activity patterns. Here we explore …

Principles of human movement augmentation and the challenges in making it a reality

J Eden, M Bräcklein, J Ibáñez, DY Barsakcioglu… - Nature …, 2022 - nature.com
Augmenting the body with artificial limbs controlled concurrently to one's natural limbs has
long appeared in science fiction, but recent technological and neuroscientific advances …