Despite colossal achievements in antibiotic therapy in recent decades, drug-resistant
pathogens have remained a leading cause of death and economic loss globally. One such …

The issue of antimicrobial resistance is becoming an increasingly serious challenge in both
human and veterinary medicine. Prudent antimicrobial use in veterinary medicine is …

l-Phenylalanine (l-Phe) is widely used in the food and pharmaceutical industries. However,
the biosynthesis of l-Phe using Escherichia coli remains challenging due to its lower …

Many antibiotics that are used in healthcare, farming, and aquaculture end up in
environments with different spatial structures that might promote heterogeneity in the …

Gram-negative bacteria, such as Escherichia coli, are characterized by an asymmetric outer
membrane (OM) with lipopolysaccharide (LPS) located in the outer leaflet and …

The aim of this study was to determine if acrAB induction in Salmonella Typhimurium relies
solely on RamA or if other transcriptional activator pathways are also involved, and to better …

Piperacillin-Tazobactam is a β-lactam/β-lactamase inhibitor combination which is amongst
the most prescribed antimicrobials in hospital medicine. Piperacillin is inactivated by …

This is the first edition of Microbial Musings since Microbiology moved to a fully open access
(OA) format, so this may be the first time you are reading Musings. Here, editors highlight …

To mark the 40 year anniversary of the seminal description of antibiotic efflux pumps in
bacteria [1] and the 30 year milestone of the characterization of the resistance-nodulation …

Phenylalanine arginine β‐naphthylamine, or PAβN, is a C‐terminus capped dipeptide
discovered in 1999 as an RND‐type efflux pump inhibitor (EPI). Since then, PAβN has …