Structure and applications of PIC-based polymers and hydrogels
Over the last decade, water-soluble polyisocyanopeptides (PICs) have emerged as a new
class of biomimetic polymers. Analogous to biopolymers, PICs exhibit a semi-flexible nature; …
class of biomimetic polymers. Analogous to biopolymers, PICs exhibit a semi-flexible nature; …
[HTML][HTML] Injectable polyisocyanide hydrogel as healing supplement for connective tissue regeneration in an abdominal wound model
AN Gudde, MJJ van Velthoven, PHJ Kouwer… - Biomaterials, 2023 - Elsevier
In pelvic organ prolapse (POP) patients, the uterus, bladder and/or rectum descends into
vagina due to weakened support tissues. High recurrence rates after POP surgery suggest …
vagina due to weakened support tissues. High recurrence rates after POP surgery suggest …
Reassessing human MHC-I genetic diversity in T cell studies
Abstract The Major Histocompatibility Complex class I (MHC-I) system plays a vital role in
immune responses by presenting antigens to T cells. Allele specific technologies, including …
immune responses by presenting antigens to T cells. Allele specific technologies, including …
Monitoring Cell Proliferation by Dye Dilution: Considerations for Panel Design
JD Tario Jr, KT Soh, PK Wallace, KA Muirhead - Flow Cytometry Protocols, 2024 - Springer
High dimensional studies that include proliferation dyes face two inherent challenges in
panel design. First, the more rounds of cell division to be monitored based on dye dilution …
panel design. First, the more rounds of cell division to be monitored based on dye dilution …
Emerging approaches for T cell-stimulating platform development
E Ariail, NG Espinoza, AC Stephenson, JB Spangler - Cell Systems, 2024 - cell.com
T cells are key mediators of the adaptive immune response, playing both direct and
supporting roles in the destruction of foreign pathogenic threats as well as pathologically …
supporting roles in the destruction of foreign pathogenic threats as well as pathologically …
[HTML][HTML] Interleukin-12 decorated nanosized semiflexible Immunofilaments enable directed targeting and augmented IFNγ responses of natural killer cells
L Weiss, M Schluck, R Classens, PKJD de Jonge… - Acta Biomaterialia, 2024 - Elsevier
Immunotherapies are a powerful strategy to treat cancer by modulating the immune system
to raise an anti-tumor immune response. A prime example of immunotherapies are cytokines …
to raise an anti-tumor immune response. A prime example of immunotherapies are cytokines …
Immunofilaments Are Well Tolerated after Local or Systemic Administration in Mice
L Weiss, R Classens, M Schluck, E Grad… - ACS Pharmacology & …, 2024 - ACS Publications
The invention of nanosized biomaterials has paved the way for novel therapeutics that can
manipulate cells on a nanoscale. Nanosized immunofilaments (IFs) are synthetic …
manipulate cells on a nanoscale. Nanosized immunofilaments (IFs) are synthetic …
Nanomaterial‐Based Strategies for Preventing Tumor Metastasis by Interrupting the Metastatic Biological Processes
Q Cai, Y He, Y Zhou, J Zheng… - Advanced Healthcare …, 2024 - Wiley Online Library
Tumor metastasis is the primary cause of cancer‐related deaths. The prevention of tumor
metastasis has garnered notable interest and interrupting metastatic biological processes is …
metastasis has garnered notable interest and interrupting metastatic biological processes is …
The DC–T cell axis is an effective target for the treatment of non‐small cell lung cancer
S Wang, G Zhang, Q Cui, Y Yang… - Immunity …, 2023 - Wiley Online Library
The dendritic cell (DC)‐T cell axis is a bridge that connects innate and adaptive immunities.
The initial immune response against tumors is mainly induced by mature antigen‐presenting …
The initial immune response against tumors is mainly induced by mature antigen‐presenting …
Crosstalking with dendritic cells: a path to engineer advanced T Cell immunotherapy
Crosstalk between dendritic cells and T cells plays a crucial role in modulating immune
responses in natural and pathological conditions. DC-T cell crosstalk is achieved through …
responses in natural and pathological conditions. DC-T cell crosstalk is achieved through …