Midlobular hepatocytes are proposed to be the most plastic hepatic cell, providing a
reservoir for hepatocyte proliferation during homeostasis and regeneration. However, other …

Saturated fatty acids (SFAs)(the" bad" fat), especially palmitate (PA), in the human diet are
blamed for potential health risks such as obesity and cancer because of SFA-induced …

Maternal obesity predisposes for hepato-metabolic disorders early in life. However, the
underlying mechanisms causing early onset dysfunction of the liver and metabolism remain …

Acute liver failure (ALF) is a significant global issue with elevated morbidity and mortality
rates. There is an urgent and pressing need for secure and effective treatments. Ferroptosis …

In preeclampsia (PE), impaired trophoblast proliferation and differentiation are thought to
cause abnormal placentation and subsequent clinical manifestations of the disease, ie …

Heat-stress (HS) leads to impaired gut health, adversely affecting milk production of dairy
cows. In the present study, we investigated the protective effects of tea polyphenols (TP) …

Acute liver injury (ALI) is a rapid pathological process that may cause severe liver disease
and may even be life‐threatening. During ALI, the function of males absent on the first (MOF) …

Excessive production of transforming growth factor-β1 (TGF-β1) and its binding to
transforming growth factor-β receptor type II (TGF-βRII) promotes fibrosis by activation of the …

Одно из важнейших направлений в современной геронауке—поиск биомеханизмов
старения и геропротективных методов. В последние годы все большее внимание стало …

Insulin-like growth factor I (IGF-I) is an anabolic growth hormone indispensable for cell
growth, proliferation, differentiation, and other metabolic processes. Three missense …